Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 679259..679838 Replicon chromosome
Accession NC_013173
Organism Desulfomicrobium baculatum DSM 4028

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DBAC_RS03120 Protein ID WP_015772831.1
Coordinates 679551..679838 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DBAC_RS03115 Protein ID WP_174263015.1
Coordinates 679259..679543 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBAC_RS03085 674567..675544 + 978 WP_015772823.1 4Fe-4S binding protein -
DBAC_RS03090 675555..676610 - 1056 WP_015772824.1 ribosome small subunit-dependent GTPase A -
DBAC_RS03095 676619..677329 - 711 WP_015772825.1 methyltransferase domain-containing protein -
DBAC_RS03100 677444..677719 - 276 WP_015772826.1 hypothetical protein -
DBAC_RS03105 677993..678577 - 585 WP_015772828.1 class I SAM-dependent methyltransferase -
DBAC_RS03115 679259..679543 - 285 WP_174263015.1 putative addiction module antidote protein Antitoxin
DBAC_RS03120 679551..679838 - 288 WP_015772831.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DBAC_RS03125 680084..680944 - 861 WP_015772832.1 paraslipin -
DBAC_RS03130 680954..681418 - 465 WP_015772833.1 NfeD family protein -
DBAC_RS03135 681686..682453 + 768 WP_015772834.1 IclR family transcriptional regulator -
DBAC_RS03140 682650..683789 + 1140 WP_043810275.1 ABC transporter substrate-binding protein -
DBAC_RS03145 683865..684758 + 894 WP_015772836.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-82)

Antitoxin

Uncharacterized protein HI1420

(2-91)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10876.51 Da        Isoelectric Point: 10.8871

>T24230 WP_015772831.1 NC_013173:c679838-679551 [Desulfomicrobium baculatum DSM 4028]
MNTVYRSSLFDSWLRSLRDKAAQARIFNRIRNVELGNLGDYKTLGGGLFELRVHHGPGYRLYFTRNGETVVFLLAGGEKS
TQGKDILRARKLMEK

Download         Length: 288 bp

>T24230 NC_013173:c679838-679551 [Desulfomicrobium baculatum DSM 4028]
ATGAACACGGTGTACCGATCCTCCCTGTTTGACTCGTGGTTGCGATCCCTGCGTGACAAGGCTGCGCAGGCCCGCATTTT
CAACCGCATCCGGAATGTCGAGCTAGGCAACCTTGGAGACTACAAAACCCTTGGCGGCGGGCTATTCGAATTGCGCGTGC
ATCACGGACCGGGATACCGTTTGTACTTCACCCGGAATGGGGAGACAGTCGTCTTCCTGCTGGCTGGCGGGGAAAAGTCT
ACTCAAGGCAAGGATATCCTCCGAGCCCGAAAATTGATGGAGAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10517.10 Da        Isoelectric Point: 5.8630

>AT24230 WP_174263015.1 NC_013173:c679543-679259 [Desulfomicrobium baculatum DSM 4028]
MTKFERFDVVDYLDNEEVIAEYLTAAMEDPDPDMFLRAVADVARARGMTKLAQDSGLGRESLYKALRPGSKPRYETVSKI
LTALNVKIKAVPAH

Download         Length: 285 bp

>AT24230 NC_013173:c679543-679259 [Desulfomicrobium baculatum DSM 4028]
ATGACAAAATTCGAGCGCTTCGACGTGGTGGATTATCTCGACAACGAAGAGGTCATCGCGGAATATCTCACCGCCGCGAT
GGAAGACCCGGACCCGGACATGTTCCTGCGAGCCGTCGCGGACGTGGCCCGCGCGCGCGGCATGACCAAGTTGGCGCAAG
ACTCCGGACTTGGCCGTGAGAGCCTGTACAAGGCTCTGCGCCCTGGCTCCAAGCCCCGCTACGAAACCGTAAGCAAAATA
CTGACTGCGCTGAACGTTAAGATCAAGGCTGTTCCTGCGCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References