Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071313..2071458 Replicon chromosome
Accession NZ_CP095426
Organism Klebsiella pneumoniae strain IM029

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071349..2071451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071313..2071458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWR69_RS10230 (MWR69_10215) 2066443..2068503 + 2061 WP_004151449.1 oligopeptidase B -
MWR69_RS10235 (MWR69_10220) 2068507..2069166 - 660 WP_002911407.1 exodeoxyribonuclease X -
MWR69_RS10240 (MWR69_10225) 2069245..2069475 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MWR69_RS10245 (MWR69_10230) 2069588..2069962 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MWR69_RS10250 (MWR69_10235) 2069966..2070835 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
MWR69_RS10255 (MWR69_10240) 2070852..2071190 + 339 WP_002911404.1 YebY family protein -
- 2071313..2071458 - 146 - - Antitoxin
- 2071349..2071451 + 103 - - Toxin
MWR69_RS10260 (MWR69_10245) 2071826..2071969 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MWR69_RS10265 (MWR69_10250) 2072074..2073042 - 969 WP_004151446.1 VirK/YbjX family protein -
MWR69_RS10270 (MWR69_10255) 2073199..2073852 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MWR69_RS10275 (MWR69_10260) 2073849..2074040 - 192 WP_002911395.1 YebW family protein -
MWR69_RS10280 (MWR69_10265) 2074138..2074377 - 240 WP_002911393.1 YebV family protein -
MWR69_RS10285 (MWR69_10270) 2074493..2075926 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241953 NZ_CP095426:2071349-2071451 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241953 NZ_CP095426:c2071458-2071313 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References