Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 5254181..5254728 Replicon chromosome
Accession NZ_CP095413
Organism Muricauda sp. SCSIO 64092

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag L0P88_RS21985 Protein ID WP_247132026.1
Coordinates 5254429..5254728 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag L0P88_RS21980 Protein ID WP_247132025.1
Coordinates 5254181..5254432 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0P88_RS21960 (L0P88_21960) 5251090..5251254 - 165 WP_247132021.1 type II toxin-antitoxin system HicB family antitoxin -
L0P88_RS21965 (L0P88_21965) 5251274..5252065 - 792 WP_247132022.1 AAA family ATPase -
L0P88_RS21970 (L0P88_21970) 5252074..5252661 - 588 WP_247132023.1 recombinase family protein -
L0P88_RS21975 (L0P88_21975) 5252782..5253396 - 615 WP_247132024.1 tyrosine-type recombinase/integrase -
L0P88_RS21980 (L0P88_21980) 5254181..5254432 + 252 WP_247132025.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
L0P88_RS21985 (L0P88_21985) 5254429..5254728 + 300 WP_247132026.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0P88_RS21990 (L0P88_21990) 5254882..5255406 + 525 WP_247132027.1 hypothetical protein -
L0P88_RS21995 (L0P88_21995) 5255497..5255778 - 282 WP_247132028.1 transposase -
L0P88_RS22000 (L0P88_22000) 5256077..5257087 - 1011 WP_247132029.1 transposase -
L0P88_RS22005 (L0P88_22005) 5257338..5258240 + 903 WP_247132030.1 hypothetical protein -
L0P88_RS22010 (L0P88_22010) 5258406..5259143 + 738 WP_247132031.1 hypothetical protein -
L0P88_RS22015 (L0P88_22015) 5259271..5259423 + 153 WP_247132032.1 addiction module protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-69)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12208.75 Da        Isoelectric Point: 5.2344

>T241919 WP_247132026.1 NZ_CP095413:5254429-5254728 [Muricauda sp. SCSIO 64092]
MNYKVSQEANRDIENIWLYTYENWSLEQADRYFNLIMDEIEYLAENPESGKDYSDVRKGYFRSRIKSHFIFYKINRMKEE
IEIIRVLHQRMDIESRLNG

Download         Length: 300 bp

>T241919 NZ_OU701449:217664-217771 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CATGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9586.06 Da        Isoelectric Point: 10.3911

>AT241919 WP_247132025.1 NZ_CP095413:5254181-5254432 [Muricauda sp. SCSIO 64092]
MAKNTSILLGDYFDNFISRQIKTGKYSSASEVVRAALRMFEHEESKKAELIKELKKGEKSGFIDNFDRKKLLKNLHQKHL
TGQ

Download         Length: 252 bp

>AT241919 NZ_OU701449:c217615-217552 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References