Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2294582..2294850 Replicon chromosome
Accession NZ_CP095271
Organism Escherichia coli strain EC9682

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2294710..2294812 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2294582..2294850 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU524_RS11205 2291136..2291798 - 663 WP_000944256.1 exodeoxyribonuclease X -
MU524_RS11210 2291821..2292477 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
MU524_RS11215 2292579..2292809 - 231 WP_000916763.1 DNA polymerase III subunit theta -
MU524_RS11220 2292948..2293322 + 375 WP_000168747.1 CopC domain-containing protein YobA -
MU524_RS11225 2293326..2294198 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
MU524_RS11230 2294211..2294552 + 342 WP_000984819.1 YebY family protein -
- 2294582..2294850 - 269 - - Antitoxin
- 2294710..2294812 + 103 - - Toxin
MU524_RS11235 2294947..2295603 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
MU524_RS11240 2295604..2295795 - 192 WP_001296140.1 YebW family protein -
MU524_RS11245 2295900..2296136 - 237 WP_001295499.1 YebV family protein -
MU524_RS11250 2296254..2297693 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241841 NZ_CP095271:2294710-2294812 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT241841 NZ_CP095271:c2294850-2294582 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References