Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4376045..4376190 Replicon chromosome
Accession NZ_CP095253
Organism Klebsiella pneumoniae strain 21080937

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4376081..4376183 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4376045..4376190 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU320_RS21290 (MU320_21290) 4371175..4373235 + 2061 WP_004151449.1 oligopeptidase B -
MU320_RS21295 (MU320_21295) 4373239..4373898 - 660 WP_002911407.1 exodeoxyribonuclease X -
MU320_RS21300 (MU320_21300) 4373977..4374207 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MU320_RS21305 (MU320_21305) 4374320..4374694 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MU320_RS21310 (MU320_21310) 4374698..4375567 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
MU320_RS21315 (MU320_21315) 4375584..4375922 + 339 WP_002911404.1 YebY family protein -
- 4376045..4376190 - 146 - - Antitoxin
- 4376081..4376183 + 103 - - Toxin
MU320_RS21320 (MU320_21320) 4376558..4376701 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MU320_RS21325 (MU320_21325) 4376806..4377774 - 969 WP_004151446.1 VirK/YbjX family protein -
MU320_RS21330 (MU320_21330) 4377931..4378584 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MU320_RS21335 (MU320_21335) 4378581..4378772 - 192 WP_002911395.1 YebW family protein -
MU320_RS21340 (MU320_21340) 4378870..4379109 - 240 WP_002911393.1 YebV family protein -
MU320_RS21345 (MU320_21345) 4379225..4380658 - 1434 WP_101345779.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241790 NZ_CP095253:4376081-4376183 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241790 NZ_CP095253:c4376190-4376045 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References