Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2023128..2023273 | Replicon | chromosome |
| Accession | NZ_CP095247 | ||
| Organism | Klebsiella pneumoniae strain 21080534 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2023164..2023266 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2023128..2023273 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MU311_RS09900 (MU311_09900) | 2018258..2020318 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| MU311_RS09905 (MU311_09905) | 2020322..2020981 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| MU311_RS09910 (MU311_09910) | 2021060..2021290 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| MU311_RS09915 (MU311_09915) | 2021403..2021777 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| MU311_RS09920 (MU311_09920) | 2021781..2022650 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| MU311_RS09925 (MU311_09925) | 2022667..2023005 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2023128..2023273 | - | 146 | - | - | Antitoxin |
| - | 2023164..2023266 | + | 103 | - | - | Toxin |
| MU311_RS09930 (MU311_09930) | 2023641..2023784 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| MU311_RS09935 (MU311_09935) | 2023889..2024857 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| MU311_RS09940 (MU311_09940) | 2025014..2025667 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| MU311_RS09945 (MU311_09945) | 2025664..2025855 | - | 192 | WP_002911395.1 | YebW family protein | - |
| MU311_RS09950 (MU311_09950) | 2025953..2026192 | - | 240 | WP_002911393.1 | YebV family protein | - |
| MU311_RS09955 (MU311_09955) | 2026308..2027741 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T241756 NZ_CP095247:2023164-2023266 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT241756 NZ_CP095247:c2023273-2023128 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
