Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 457052..458206 Replicon chromosome
Accession NC_012997
Organism Teredinibacter turnerae T7901

Toxin (Protein)


Gene name - Uniprot ID C5BMV7
Locus tag TERTU_RS01960 Protein ID WP_015819372.1
Coordinates 457442..458206 (+) Length 255 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID C5BMV6
Locus tag TERTU_RS01955 Protein ID WP_015820127.1
Coordinates 457052..457441 (+) Length 130 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TERTU_RS01930 453462..454310 + 849 WP_015820761.1 peptidyl-prolyl cis-trans isomerase -
TERTU_RS01935 454312..455280 + 969 WP_015820199.1 HupE/UreJ family protein -
TERTU_RS01940 455285..455887 + 603 WP_015818006.1 HupE/UreJ family protein -
TERTU_RS01945 455884..456477 + 594 WP_015819301.1 HupE/UreJ family protein -
TERTU_RS01950 456474..456884 - 411 WP_015817410.1 hypothetical protein -
TERTU_RS01955 457052..457441 + 390 WP_015820127.1 DUF2384 domain-containing protein Antitoxin
TERTU_RS01960 457442..458206 + 765 WP_015819372.1 RES family NAD+ phosphorylase Toxin
TERTU_RS01965 458327..458872 + 546 WP_015818323.1 glutathione peroxidase -
TERTU_RS01970 458934..460130 - 1197 WP_015819775.1 PHB depolymerase family esterase -
TERTU_RS01975 460428..461477 + 1050 WP_041590015.1 hypothetical protein -
TERTU_RS01980 461614..462567 - 954 WP_041590016.1 family 15 carbohydrate-binding domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(63-212)

Antitoxin

(23-47)


Sequences


Toxin        


Download         Length: 255 a.a.        Molecular weight: 28159.92 Da        Isoelectric Point: 5.7110

>T24173 WP_015819372.1 NC_012997:457442-458206 [Teredinibacter turnerae T7901]
VQIAESVSQLPIALVPLVGLAWRVVETQGTAATRAITRNADEQLRLEQLLEGCKPPVPDACEKLSYLLATPFRYPPLRHG
SRYGTRWERGIFYAAQEQETALAETAVYLWLFQQGAVEMGPLAEITDARTVFSVRLRTGRGCDLAANHFQHIQAKLTEPG
NWGYTQALGTRLREMGADFFWFPSARLAGGTNVAVVNPESFASPTPDTQQLWNLRLTPELCWFGRADAGRDTSGYFEFSR
EVFAEAGALAHPCL

Download         Length: 765 bp

>T24173 NC_012997:457442-458206 [Teredinibacter turnerae T7901]
GTGCAGATTGCCGAAAGTGTCAGCCAGTTACCGATAGCGCTGGTTCCGCTGGTAGGGCTTGCATGGCGTGTTGTTGAAAC
CCAGGGTACGGCAGCCACCCGCGCGATTACCCGCAATGCGGACGAACAGTTGCGCCTGGAGCAATTGTTGGAAGGTTGTA
AGCCGCCCGTGCCCGATGCGTGCGAAAAGCTGTCCTATTTATTGGCGACGCCTTTCCGTTACCCCCCGTTACGCCACGGT
TCACGCTATGGTACCCGCTGGGAGCGAGGAATTTTTTATGCGGCCCAGGAGCAGGAAACCGCACTGGCAGAAACGGCGGT
TTACTTGTGGCTGTTTCAGCAGGGTGCGGTGGAGATGGGCCCATTGGCTGAAATCACCGATGCGCGCACTGTATTTTCTG
TGCGACTGCGCACAGGTCGCGGCTGCGACCTGGCGGCAAACCACTTTCAGCATATTCAAGCCAAACTAACCGAGCCCGGC
AATTGGGGGTACACCCAGGCGTTGGGTACTCGGCTGCGGGAAATGGGGGCAGATTTTTTCTGGTTTCCGTCGGCGCGTTT
AGCCGGGGGCACCAACGTCGCCGTGGTTAATCCAGAGAGTTTTGCCAGCCCGACCCCAGATACTCAGCAATTGTGGAATT
TACGGCTCACACCTGAATTATGCTGGTTTGGCAGGGCAGATGCCGGACGTGACACGAGCGGCTATTTTGAGTTCAGCCGC
GAAGTGTTCGCCGAGGCTGGCGCGCTGGCGCACCCGTGCCTGTAA

Antitoxin


Download         Length: 130 a.a.        Molecular weight: 14042.40 Da        Isoelectric Point: 9.5513

>AT24173 WP_015820127.1 NC_012997:457052-457441 [Teredinibacter turnerae T7901]
MKPSIVQSDSAIVANALLDACPSLGITQDQLAQVLGVSRATVARIKKKASTHQADEAIAPSSKPFELALLVIRVYRSLYA
IVGGNVDAMKHWMNTPNHHLNLQKPIDLIQTALGLSEVIWYLDAMRGKI

Download         Length: 390 bp

>AT24173 NC_012997:457052-457441 [Teredinibacter turnerae T7901]
ATGAAGCCGTCCATTGTGCAGAGTGATAGCGCGATTGTTGCCAATGCGTTACTCGATGCCTGTCCATCTCTGGGGATCAC
CCAGGATCAGTTGGCTCAGGTACTCGGCGTTTCCCGCGCAACGGTGGCGCGCATTAAGAAAAAGGCCAGCACCCATCAGG
CCGATGAAGCGATCGCCCCCAGCAGCAAGCCGTTTGAGCTGGCGCTGCTGGTTATTCGTGTTTACCGCTCGCTCTACGCC
ATTGTAGGTGGCAACGTCGATGCGATGAAACACTGGATGAACACGCCAAACCACCATCTCAATTTACAGAAGCCCATCGA
CCTCATTCAAACCGCTCTGGGCCTCAGCGAAGTCATCTGGTATCTGGATGCCATGCGGGGAAAAATTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C5BMV7


Antitoxin

Source ID Structure
AlphaFold DB C5BMV6

References