Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1022033..1022178 | Replicon | chromosome |
| Accession | NZ_CP095240 | ||
| Organism | Klebsiella pneumoniae strain 21080237 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1022040..1022142 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1022033..1022178 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MU300_RS05120 (MU300_05115) | 1017565..1018998 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| MU300_RS05125 (MU300_05120) | 1019114..1019353 | + | 240 | WP_002911393.1 | YebV family protein | - |
| MU300_RS05130 (MU300_05125) | 1019451..1019642 | + | 192 | WP_002911395.1 | YebW family protein | - |
| MU300_RS05135 (MU300_05130) | 1019639..1020292 | - | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| MU300_RS05140 (MU300_05135) | 1020449..1021417 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| MU300_RS05145 (MU300_05140) | 1021522..1021665 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 1022033..1022178 | + | 146 | - | - | Antitoxin |
| - | 1022040..1022142 | - | 103 | - | - | Toxin |
| MU300_RS05150 (MU300_05145) | 1022301..1022639 | - | 339 | WP_002911404.1 | YebY family protein | - |
| MU300_RS05155 (MU300_05150) | 1022656..1023525 | - | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| MU300_RS05160 (MU300_05155) | 1023529..1023903 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| MU300_RS05165 (MU300_05160) | 1024016..1024246 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| MU300_RS05170 (MU300_05165) | 1024325..1024984 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| MU300_RS05175 (MU300_05170) | 1024988..1027048 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T241727 NZ_CP095240:c1022142-1022040 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT241727 NZ_CP095240:1022033-1022178 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
