Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4392390..4392535 Replicon chromosome
Accession NZ_CP095234
Organism Klebsiella pneumoniae strain 21072329

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4392426..4392528 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4392390..4392535 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU289_RS21375 (MU289_21375) 4387520..4389580 + 2061 WP_004151449.1 oligopeptidase B -
MU289_RS21380 (MU289_21380) 4389584..4390243 - 660 WP_002911407.1 exodeoxyribonuclease X -
MU289_RS21385 (MU289_21385) 4390322..4390552 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MU289_RS21390 (MU289_21390) 4390665..4391039 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MU289_RS21395 (MU289_21395) 4391043..4391912 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
MU289_RS21400 (MU289_21400) 4391929..4392267 + 339 WP_002911404.1 YebY family protein -
- 4392390..4392535 - 146 - - Antitoxin
- 4392426..4392528 + 103 - - Toxin
MU289_RS21405 (MU289_21405) 4392903..4393046 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MU289_RS21410 (MU289_21410) 4393151..4394119 - 969 WP_004151446.1 VirK/YbjX family protein -
MU289_RS21415 (MU289_21415) 4394276..4394929 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MU289_RS21420 (MU289_21420) 4394926..4395117 - 192 WP_002911395.1 YebW family protein -
MU289_RS21425 (MU289_21425) 4395215..4395454 - 240 WP_002911393.1 YebV family protein -
MU289_RS21430 (MU289_21430) 4395570..4397003 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241710 NZ_CP095234:4392426-4392528 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241710 NZ_CP095234:c4392535-4392390 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References