Detailed information of TA system TA241699

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 889897..890462
• Replicon: chromosome
• Accession: NZ_CP095187
• Organism: Pseudoxanthomonas sp. F37

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MUU77_RS04075
• Protein ID: WP_245091883.1
• Coordinates: 890208..890462 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MUU77_RS04070
• Protein ID: WP_245091881.1
• Coordinates: 889897..890154 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUU77_RS04040 (MUU77_04040)	884957..885421	+	465	WP_245091869.1	DUF6265 family protein	-
MUU77_RS04045 (MUU77_04045)	885425..886399	-	975	WP_245091871.1	cysteine synthase A	-
MUU77_RS04050 (MUU77_04050)	886421..887875	-	1455	WP_245091873.1	siroheme synthase CysG	-
MUU77_RS04055 (MUU77_04055)	888048..889031	+	984	WP_245091875.1	LysR family transcriptional regulator	-
MUU77_RS04060 (MUU77_04060)	889157..889504	+	348	WP_245091877.1	hypothetical protein	-
MUU77_RS04065 (MUU77_04065)	889501..889878	+	378	WP_245091879.1	DUF2809 domain-containing protein	-
MUU77_RS04070 (MUU77_04070)	889897..890154	+	258	WP_245091881.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
MUU77_RS04075 (MUU77_04075)	890208..890462	+	255	WP_245091883.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MUU77_RS04080 (MUU77_04080)	890469..890837	-	369	WP_245091884.1	hypothetical protein	-
MUU77_RS04085 (MUU77_04085)	890948..891718	-	771	WP_245091886.1	LytTR family DNA-binding domain-containing protein	-
MUU77_RS04090 (MUU77_04090)	891715..892977	-	1263	WP_245094208.1	histidine kinase	-
MUU77_RS04095 (MUU77_04095)	893118..893831	-	714	WP_245091892.1	phosphoadenylyl-sulfate reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (10-68)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9788.41 Da
• Isoelectric Point: 12.1370

>T241699 WP_245091883.1 NZ_CP095187:890208-890462 [Pseudoxanthomonas sp. F37]
VDNRAAAIERVRRVFAHVDHLADHPDSGRRPPELKRGRYRQIVEPPCRVFHRSEPGRVLILHVMRSERLLRPGMLQARKP
GKAR

Nucleotide

• Length: 255 bp

>T241699 NZ_OD940434:595249-595365 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9375.80 Da
• Isoelectric Point: 9.2325

>AT241699 WP_245091881.1 NZ_CP095187:889897-890154 [Pseudoxanthomonas sp. F37]
MRTELVTTLKRQATGLLADVERDRQPILITQHGLPSAYRVDVETCETLLSRMAVLEGIARGEQAVAEGRAVAHPQARDRL
ARGLK

Nucleotide

• Length: 258 bp

>AT241699 NZ_OD940434:c595481-595276 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC