Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicA |
| Location | 2188595..2189007 | Replicon | chromosome |
| Accession | NZ_CP095186 | ||
| Organism | Pseudoxanthomonas mexicana strain F31 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | MUU75_RS10345 | Protein ID | WP_245089684.1 |
| Coordinates | 2188813..2189007 (-) | Length | 65 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | MUU75_RS10340 | Protein ID | WP_245089681.1 |
| Coordinates | 2188595..2188807 (-) | Length | 71 a.a. |
Genomic Context
Location: 2187034..2187279 (246 bp)
Type: Others
Protein ID: WP_245089675.1
Type: Others
Protein ID: WP_245089675.1
Location: 2185750..2186142 (393 bp)
Type: Others
Protein ID: Protein_2025
Type: Others
Protein ID: Protein_2025
Location: 2186145..2186348 (204 bp)
Type: Others
Protein ID: Protein_2026
Type: Others
Protein ID: Protein_2026
Location: 2186410..2186841 (432 bp)
Type: Others
Protein ID: WP_245089672.1
Type: Others
Protein ID: WP_245089672.1
Location: 2187461..2188555 (1095 bp)
Type: Others
Protein ID: WP_245089678.1
Type: Others
Protein ID: WP_245089678.1
Location: 2188595..2188807 (213 bp)
Type: Antitoxin
Protein ID: WP_245089681.1
Type: Antitoxin
Protein ID: WP_245089681.1
Location: 2188813..2189007 (195 bp)
Type: Toxin
Protein ID: WP_245089684.1
Type: Toxin
Protein ID: WP_245089684.1
Location: 2189100..2191793 (2694 bp)
Type: Others
Protein ID: WP_245089687.1
Type: Others
Protein ID: WP_245089687.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUU75_RS10315 (MUU75_10315) | 2185750..2186142 | - | 393 | Protein_2025 | pyruvate dehydrogenase (acetyl-transferring), homodimeric type | - |
| MUU75_RS10320 (MUU75_10320) | 2186145..2186348 | - | 204 | Protein_2026 | DUF3817 domain-containing protein | - |
| MUU75_RS10325 (MUU75_10325) | 2186410..2186841 | - | 432 | WP_245089672.1 | hypothetical protein | - |
| MUU75_RS10330 (MUU75_10330) | 2187034..2187279 | + | 246 | WP_245089675.1 | helix-turn-helix transcriptional regulator | - |
| MUU75_RS10335 (MUU75_10335) | 2187461..2188555 | - | 1095 | WP_245089678.1 | crosslink repair DNA glycosylase YcaQ family protein | - |
| MUU75_RS10340 (MUU75_10340) | 2188595..2188807 | - | 213 | WP_245089681.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| MUU75_RS10345 (MUU75_10345) | 2188813..2189007 | - | 195 | WP_245089684.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| MUU75_RS10350 (MUU75_10350) | 2189100..2191793 | - | 2694 | WP_245089687.1 | pyruvate dehydrogenase (acetyl-transferring), homodimeric type | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2184639..2196202 | 11563 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 6849.91 Da Isoelectric Point: 11.3688
>T241697 WP_245089684.1 NZ_CP095186:c2189007-2188813 [Pseudoxanthomonas mexicana]
VPPKIRDVLQQLKDAGWQQVGQTGSHRQFKHPTLPGRVTVAGKPGDDVAPGTLASILKQAGIKR
VPPKIRDVLQQLKDAGWQQVGQTGSHRQFKHPTLPGRVTVAGKPGDDVAPGTLASILKQAGIKR
Download Length: 195 bp
>T241697 NZ_OD940434:c127373-126735 [Enterococcus faecalis]
ATGATACTAAATAAGAAAAAATTATATTTCGAAACACAGGCATTTACTGACAAACTTATAAATGAAATTTCAATCAATAT
GTCTAAAAGAAAAGAACTCATCAATTGTTATGATATTGAAGCCTACGTAAAAGAAACCGAAAACATTGATTTTTTTGATT
ATCCATTCAAAAAACAATCTAAAAAATTAATCTGGGGATCAGTAACAAAAATTGGTGATGTAACTATGGTAGCGACTGCC
CAACACTTGAAAATAGAAATTAAAAATTTTACGAAAATGCACGAAATAATTCATCATTATTTTGACTATACGACAGATAT
GCCTAACAATGAAAAATCATTTGATACACTACTTATAAAAAAGGGCTATCTTCCTGAAGATTATCCTAAAGAATTCAGAG
CAAATAAGGGTGCCGGAATGTTACTTATTAATAAAAAAGCCTTAAAGTATGCATTTAGTACTTATGATGATCTTGAAAAA
ATGGCTAGTTTTTTCAACGTAAACGATATAGTTCTCAAGATAAGAATTCTTGACGAATTAATCTATTCCCACAACTTATC
TTATAAACAAGCCAATCTTATTTATAATAGTTACTATTTTCAACAACAAACACAACTTAAAGAGATTTTACTCAAATAA
ATGATACTAAATAAGAAAAAATTATATTTCGAAACACAGGCATTTACTGACAAACTTATAAATGAAATTTCAATCAATAT
GTCTAAAAGAAAAGAACTCATCAATTGTTATGATATTGAAGCCTACGTAAAAGAAACCGAAAACATTGATTTTTTTGATT
ATCCATTCAAAAAACAATCTAAAAAATTAATCTGGGGATCAGTAACAAAAATTGGTGATGTAACTATGGTAGCGACTGCC
CAACACTTGAAAATAGAAATTAAAAATTTTACGAAAATGCACGAAATAATTCATCATTATTTTGACTATACGACAGATAT
GCCTAACAATGAAAAATCATTTGATACACTACTTATAAAAAAGGGCTATCTTCCTGAAGATTATCCTAAAGAATTCAGAG
CAAATAAGGGTGCCGGAATGTTACTTATTAATAAAAAAGCCTTAAAGTATGCATTTAGTACTTATGATGATCTTGAAAAA
ATGGCTAGTTTTTTCAACGTAAACGATATAGTTCTCAAGATAAGAATTCTTGACGAATTAATCTATTCCCACAACTTATC
TTATAAACAAGCCAATCTTATTTATAATAGTTACTATTTTCAACAACAAACACAACTTAAAGAGATTTTACTCAAATAA
Antitoxin
Download Length: 71 a.a. Molecular weight: 7280.29 Da Isoelectric Point: 4.1511
>AT241697 WP_245089681.1 NZ_CP095186:c2188807-2188595 [Pseudoxanthomonas mexicana]
MRYAIVIEQAGGNYSAYVPDLPGCVATGATKAEVEVLIHDAIALHLAGLREDGVAIPVPSSQVEYIDVAA
MRYAIVIEQAGGNYSAYVPDLPGCVATGATKAEVEVLIHDAIALHLAGLREDGVAIPVPSSQVEYIDVAA
Download Length: 213 bp
>AT241697 NZ_OD940434:c127754-127380 [Enterococcus faecalis]
ATGAAAACTTACGAAAAGATAAAACAATTAAGAGAAAATAGAGAAATCACTCAAAAAGAAATTTCAAACGCACTAGACAT
TAATGTTAGTGTATATAATAAAATAGAACTTGGAATACGTCCATTAAGAGAAGAAGAACTTACTGCTATTGCTGATTTTT
TTAATGTTTCAATTGATTATTTAACAGGACGCACTGATAACCCTACAACACCTTCAAATAATCAAAAAGAAGCTGGACAA
AATATTATTTCACATTTCAGATTAAACACTAATGATTTAAGTTCTGATGACATAGAAGAATTAGAAAAAGAATTGATTGA
TTTTCAAGAATTTCTTATAAAACGAGCAAAAGAAAGAAAAAAAAAGAGTGAGTAA
ATGAAAACTTACGAAAAGATAAAACAATTAAGAGAAAATAGAGAAATCACTCAAAAAGAAATTTCAAACGCACTAGACAT
TAATGTTAGTGTATATAATAAAATAGAACTTGGAATACGTCCATTAAGAGAAGAAGAACTTACTGCTATTGCTGATTTTT
TTAATGTTTCAATTGATTATTTAACAGGACGCACTGATAACCCTACAACACCTTCAAATAATCAAAAAGAAGCTGGACAA
AATATTATTTCACATTTCAGATTAAACACTAATGATTTAAGTTCTGATGACATAGAAGAATTAGAAAAAGAATTGATTGA
TTTTCAAGAATTTCTTATAAAACGAGCAAAAGAAAGAAAAAAAAAGAGTGAGTAA