Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3804940..3805597 Replicon chromosome
Accession NZ_CP095177
Organism Enterobacter hormaechei strain K528

Toxin (Protein)


Gene name cptA Uniprot ID A0A0A6GSQ9
Locus tag MUY31_RS18330 Protein ID WP_022649305.1
Coordinates 3804940..3805350 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag MUY31_RS18335 Protein ID WP_003863437.1
Coordinates 3805331..3805597 (-) Length 89 a.a.

Genomic Context


MUY31_RS18325MUY31_RS18340MUY31_RS18350MUY31_RS18355MUY31_RS18310MUY31_RS18315MUY31_RS18320MUY31_RS18330MUY31_RS18335MUY31_RS18345
Location: 3804417..3804938 (522 bp)
Type: Others
Protein ID: WP_003863440.1
Location: 3805892..3806872 (981 bp)
Type: Others
Protein ID: WP_003863435.1
Location: 3807884..3808615 (732 bp)
Type: Others
Protein ID: WP_003863431.1
Location: 3808732..3810165 (1434 bp)
Type: Others
Protein ID: WP_003863430.1
Location: 3800938..3802671 (1734 bp)
Type: Others
Protein ID: WP_048242034.1
Location: 3802677..3803390 (714 bp)
Type: Others
Protein ID: WP_048242037.1
Location: 3803419..3804315 (897 bp)
Type: Others
Protein ID: WP_003863442.1
Location: 3804940..3805350 (411 bp)
Type: Toxin
Protein ID: WP_022649305.1
Location: 3805331..3805597 (267 bp)
Type: Antitoxin
Protein ID: WP_003863437.1
Location: 3806958..3807617 (660 bp)
Type: Others
Protein ID: WP_003863433.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MUY31_RS18310 (MUY31_18310)3800938..3802671-1734WP_048242034.1single-stranded-DNA-specific exonuclease RecJ-
MUY31_RS18315 (MUY31_18315)3802677..3803390-714WP_048242037.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
MUY31_RS18320 (MUY31_18320)3803419..3804315-897WP_003863442.1site-specific tyrosine recombinase XerD-
MUY31_RS18325 (MUY31_18325)3804417..3804938+522WP_003863440.1flavodoxin FldB-
MUY31_RS18330 (MUY31_18330)3804940..3805350-411WP_022649305.1protein YgfXToxin
MUY31_RS18335 (MUY31_18335)3805331..3805597-267WP_003863437.1FAD assembly factor SdhEAntitoxin
MUY31_RS18340 (MUY31_18340)3805892..3806872+981WP_003863435.1tRNA-modifying protein YgfZ-
MUY31_RS18345 (MUY31_18345)3806958..3807617-660WP_003863433.1hemolysin III family protein-
MUY31_RS18350 (MUY31_18350)3807884..3808615+732WP_003863431.1MurR/RpiR family transcriptional regulator-
MUY31_RS18355 (MUY31_18355)3808732..3810165+1434WP_003863430.16-phospho-beta-glucosidase BglA-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T241677 WP_022649305.1 NZ_CP095177:c3805350-3804940 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAAMVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

>T241677 NZ_OD940420:2873147-2873290 [Enterococcus faecalis]
ATGAATGTAAGTGCTAAAATCTATGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT241677 WP_003863437.1 NZ_CP095177:c3805597-3805331 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT241677 NZ_OD940420:c2873481-2873223 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A0A6GSQ9


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A837F8P5

References