Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 3804940..3805597 | Replicon | chromosome |
Accession | NZ_CP095177 | ||
Organism | Enterobacter hormaechei strain K528 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A0A6GSQ9 |
Locus tag | MUY31_RS18330 | Protein ID | WP_022649305.1 |
Coordinates | 3804940..3805350 (-) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | G8LDB7 |
Locus tag | MUY31_RS18335 | Protein ID | WP_003863437.1 |
Coordinates | 3805331..3805597 (-) | Length | 89 a.a. |
Genomic Context
Location: 3804417..3804938 (522 bp)
Type: Others
Protein ID: WP_003863440.1
Type: Others
Protein ID: WP_003863440.1
Location: 3805892..3806872 (981 bp)
Type: Others
Protein ID: WP_003863435.1
Type: Others
Protein ID: WP_003863435.1
Location: 3807884..3808615 (732 bp)
Type: Others
Protein ID: WP_003863431.1
Type: Others
Protein ID: WP_003863431.1
Location: 3808732..3810165 (1434 bp)
Type: Others
Protein ID: WP_003863430.1
Type: Others
Protein ID: WP_003863430.1
Location: 3800938..3802671 (1734 bp)
Type: Others
Protein ID: WP_048242034.1
Type: Others
Protein ID: WP_048242034.1
Location: 3802677..3803390 (714 bp)
Type: Others
Protein ID: WP_048242037.1
Type: Others
Protein ID: WP_048242037.1
Location: 3803419..3804315 (897 bp)
Type: Others
Protein ID: WP_003863442.1
Type: Others
Protein ID: WP_003863442.1
Location: 3804940..3805350 (411 bp)
Type: Toxin
Protein ID: WP_022649305.1
Type: Toxin
Protein ID: WP_022649305.1
Location: 3805331..3805597 (267 bp)
Type: Antitoxin
Protein ID: WP_003863437.1
Type: Antitoxin
Protein ID: WP_003863437.1
Location: 3806958..3807617 (660 bp)
Type: Others
Protein ID: WP_003863433.1
Type: Others
Protein ID: WP_003863433.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MUY31_RS18310 (MUY31_18310) | 3800938..3802671 | - | 1734 | WP_048242034.1 | single-stranded-DNA-specific exonuclease RecJ | - |
MUY31_RS18315 (MUY31_18315) | 3802677..3803390 | - | 714 | WP_048242037.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
MUY31_RS18320 (MUY31_18320) | 3803419..3804315 | - | 897 | WP_003863442.1 | site-specific tyrosine recombinase XerD | - |
MUY31_RS18325 (MUY31_18325) | 3804417..3804938 | + | 522 | WP_003863440.1 | flavodoxin FldB | - |
MUY31_RS18330 (MUY31_18330) | 3804940..3805350 | - | 411 | WP_022649305.1 | protein YgfX | Toxin |
MUY31_RS18335 (MUY31_18335) | 3805331..3805597 | - | 267 | WP_003863437.1 | FAD assembly factor SdhE | Antitoxin |
MUY31_RS18340 (MUY31_18340) | 3805892..3806872 | + | 981 | WP_003863435.1 | tRNA-modifying protein YgfZ | - |
MUY31_RS18345 (MUY31_18345) | 3806958..3807617 | - | 660 | WP_003863433.1 | hemolysin III family protein | - |
MUY31_RS18350 (MUY31_18350) | 3807884..3808615 | + | 732 | WP_003863431.1 | MurR/RpiR family transcriptional regulator | - |
MUY31_RS18355 (MUY31_18355) | 3808732..3810165 | + | 1434 | WP_003863430.1 | 6-phospho-beta-glucosidase BglA | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 16321.21 Da Isoelectric Point: 11.4775
>T241677 WP_022649305.1 NZ_CP095177:c3805350-3804940 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAAMVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE
VVLWQSDLRVSWRSQWMSLLLHGLVAAMVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE
Download Length: 411 bp
>T241677 NZ_OD940420:2873147-2873290 [Enterococcus faecalis]
ATGAATGTAAGTGCTAAAATCTATGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
ATGAATGTAAGTGCTAAAATCTATGAAAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10526.96 Da Isoelectric Point: 4.8310
>AT241677 WP_003863437.1 NZ_CP095177:c3805597-3805331 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI
Download Length: 267 bp
>AT241677 NZ_OD940420:c2873481-2873223 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0A6GSQ9 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A837F8P5 |