Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 2560943..2561483 Replicon chromosome
Accession NZ_CP095161
Organism Avibacterium paragallinarum strain ZJ-C

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LNL76_RS12785 Protein ID WP_110479397.1
Coordinates 2561193..2561483 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LNL76_RS12780 Protein ID WP_110479398.1
Coordinates 2560943..2561203 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNL76_RS12755 2556122..2556286 - 165 WP_165816430.1 hypothetical protein -
LNL76_RS12760 2556357..2556938 + 582 WP_017806819.1 D-sedoheptulose 7-phosphate isomerase -
LNL76_RS12765 2557028..2558434 + 1407 WP_110479400.1 membrane-bound lytic murein transglycosylase MltF -
LNL76_RS12775 2559321..2560508 + 1188 WP_110479399.1 tyrosine-type recombinase/integrase -
LNL76_RS12780 2560943..2561203 + 261 WP_110479398.1 stability protein StbD Antitoxin
LNL76_RS12785 2561193..2561483 + 291 WP_110479397.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LNL76_RS12790 2562220..2562510 + 291 WP_017806817.1 co-chaperone GroES -
LNL76_RS12795 2562583..2564226 + 1644 WP_110479396.1 chaperonin GroEL -
LNL76_RS12800 2564509..2565456 - 948 WP_110479395.1 cysteine synthase A -
LNL76_RS12805 2565575..2566423 - 849 WP_110479394.1 sulfate transporter CysZ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11418.36 Da        Isoelectric Point: 10.7313

>T241606 WP_110479397.1 NZ_CP095161:2561193-2561483 [Avibacterium paragallinarum]
MTYKLSFDKRALKEWHKLGDTLRQQFKAKLIERLENPHVLSDKLHGYQTLYKIKLRSAGYRLVYDVNDNEIRVIVLSVGK
RERLQAYKKALSRKAQ

Download         Length: 291 bp

>T241606 NZ_LT992493:225675-225941 [Vibrio cholerae]
ATGATTAAATTTGAATTTGATGAAAACAAAAGCAGAAGTAATCTCGAAAAGCACGGTATTGATTTTCATACAGCTCAAGG
ATTGTGGAATGATTCAGATCTTATCGAGATCCCTGCTAACACGAGTGATGAGCCCAGATATTTGGTTGTCGGCTTACTAA
ACGGTAAGCATTGGTCAGGAGTAATTACCTACCGAGGTACGAATATCAGGATCATCTCAGTTCGGCGTTCACGGAAAGCG
GAGGTAAGCCTTTATGAAAGCGCATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9604.03 Da        Isoelectric Point: 4.3085

>AT241606 WP_110479398.1 NZ_CP095161:2560943-2561203 [Avibacterium paragallinarum]
MAIQQILTRHTASISDLKKNPMGIVSEGTEQEGAIAILNRNEPVFYCVNPRLFAVIQEILEDKELGELATQRLATLDPVE
VRLDDL

Download         Length: 261 bp

>AT241606 NZ_LT992493:225928-226173 [Vibrio cholerae]
ATGAAAGCGCATGAATTTGATGCCAAGTTTGAAAGTGACGACGATGATATCGTAATGGACTTGGATCTATCGCAAGCTAA
AAGACCGATGCATAAGCAAAAACGAGTCAATGTAGATTTTCCAGCCTGGATGCTTGAGTCCTTGGACAGAGAAGCGAGTC
GTATTGGTGTAACACGTCAATCAATCATTAAAATTTGGCTGGCAGAAAGGTTAGAGAGCGTGTCTCATCATTCAAGTGTG
AGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References