Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2035584..2035729 Replicon chromosome
Accession NZ_CP095150
Organism Klebsiella pneumoniae strain Iso00073

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2035620..2035722 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2035584..2035729 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU411_RS09780 2030714..2032774 + 2061 WP_064145333.1 oligopeptidase B -
MU411_RS09785 2032778..2033437 - 660 WP_002911407.1 exodeoxyribonuclease X -
MU411_RS09790 2033516..2033746 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MU411_RS09795 2033859..2034233 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MU411_RS09800 2034237..2035106 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MU411_RS09805 2035123..2035461 + 339 WP_002911404.1 YebY family protein -
- 2035584..2035729 - 146 - - Antitoxin
- 2035620..2035722 + 103 - - Toxin
MU411_RS09810 2036098..2036241 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MU411_RS09815 2036346..2037314 - 969 WP_004151446.1 VirK/YbjX family protein -
MU411_RS09820 2037471..2038124 + 654 WP_064145335.1 protein-serine/threonine phosphatase -
MU411_RS09825 2038121..2038312 - 192 WP_002911395.1 YebW family protein -
MU411_RS09830 2038410..2038649 - 240 WP_002911393.1 YebV family protein -
MU411_RS09835 2038765..2040198 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241543 NZ_CP095150:2035620-2035722 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241543 NZ_CP095150:c2035729-2035584 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References