Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1918408..1918553 | Replicon | chromosome |
| Accession | NZ_CP095145 | ||
| Organism | Klebsiella pneumoniae strain Iso00100 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1918444..1918546 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1918408..1918553 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MU412_RS09300 | 1913538..1915598 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| MU412_RS09305 | 1915602..1916261 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| MU412_RS09310 | 1916340..1916570 | - | 231 | WP_096903066.1 | DNA polymerase III subunit theta | - |
| MU412_RS09315 | 1916683..1917057 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| MU412_RS09320 | 1917061..1917930 | + | 870 | WP_032420215.1 | copper homeostasis membrane protein CopD | - |
| MU412_RS09325 | 1917947..1918285 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1918408..1918553 | - | 146 | - | - | Antitoxin |
| - | 1918444..1918546 | + | 103 | - | - | Toxin |
| MU412_RS09330 | 1918920..1919063 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| MU412_RS09335 | 1919168..1920136 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| MU412_RS09340 | 1920293..1920946 | + | 654 | WP_032444871.1 | protein-serine/threonine phosphatase | - |
| MU412_RS09345 | 1920943..1921134 | - | 192 | WP_002911395.1 | YebW family protein | - |
| MU412_RS09350 | 1921232..1921471 | - | 240 | WP_002911393.1 | YebV family protein | - |
| MU412_RS09355 | 1921587..1923020 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T241522 NZ_CP095145:1918444-1918546 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT241522 NZ_CP095145:c1918553-1918408 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
