Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1868791..1869062 Replicon chromosome
Accession NC_012971
Organism Escherichia coli BL21(DE3)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1868829..1868932 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1868791..1869062 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECD_RS09495 1865948..1867387 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECD_RS09500 1867505..1867741 + 237 WP_001295499.1 DUF1480 family protein -
ECD_RS09505 1867846..1868037 + 192 WP_001296140.1 YebW family protein -
ECD_RS09510 1868038..1868694 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1868791..1869062 + 272 - - Antitoxin
- 1868829..1868932 - 104 - - Toxin
ECD_RS09520 1869089..1869430 - 342 WP_000976472.1 YebY family protein -
ECD_RS09525 1869443..1870315 - 873 WP_000879293.1 copper homeostasis membrane protein CopD -
ECD_RS09530 1870319..1870693 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECD_RS09535 1870832..1871062 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECD_RS09540 1871164..1871820 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
ECD_RS09545 1871844..1872506 + 663 WP_000944245.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T24151 NC_012971:c1868932-1868829 [Escherichia coli BL21(DE3)]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT24151 NC_012971:1868791-1869062 [Escherichia coli BL21(DE3)]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References