Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974394..1974539 Replicon chromosome
Accession NZ_CP095132
Organism Klebsiella pneumoniae strain Iso00267

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974430..1974532 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974394..1974539 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU415_RS09575 1969524..1971584 + 2061 WP_004151449.1 oligopeptidase B -
MU415_RS09580 1971588..1972247 - 660 WP_002911407.1 exodeoxyribonuclease X -
MU415_RS09585 1972326..1972556 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MU415_RS09590 1972669..1973043 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MU415_RS09595 1973047..1973916 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
MU415_RS09600 1973933..1974271 + 339 WP_002911404.1 YebY family protein -
- 1974394..1974539 - 146 - - Antitoxin
- 1974430..1974532 + 103 - - Toxin
MU415_RS09605 1974907..1975050 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MU415_RS09610 1975155..1976123 - 969 WP_014907334.1 VirK/YbjX family protein -
MU415_RS09615 1976280..1976933 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
MU415_RS09620 1976930..1977121 - 192 WP_002911395.1 YebW family protein -
MU415_RS09625 1977219..1977458 - 240 WP_002911393.1 YebV family protein -
MU415_RS09630 1977574..1979007 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241453 NZ_CP095132:1974430-1974532 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241453 NZ_CP095132:c1974539-1974394 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References