Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945756..1945901 Replicon chromosome
Accession NZ_CP095121
Organism Klebsiella pneumoniae strain KP1601

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945792..1945894 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945756..1945901 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUU71_RS09415 1940886..1942946 + 2061 WP_004151449.1 oligopeptidase B -
MUU71_RS09420 1942950..1943609 - 660 WP_002911407.1 exodeoxyribonuclease X -
MUU71_RS09425 1943688..1943918 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MUU71_RS09430 1944031..1944405 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MUU71_RS09435 1944409..1945278 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MUU71_RS09440 1945295..1945633 + 339 WP_002911404.1 YebY family protein -
- 1945756..1945901 - 146 - - Antitoxin
- 1945792..1945894 + 103 - - Toxin
MUU71_RS09445 1946269..1946412 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MUU71_RS09450 1946517..1947485 - 969 WP_004151446.1 VirK/YbjX family protein -
MUU71_RS09455 1947642..1948295 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
MUU71_RS09460 1948292..1948483 - 192 WP_002911395.1 YebW family protein -
MUU71_RS09465 1948581..1948820 - 240 WP_002911393.1 YebV family protein -
MUU71_RS09470 1948936..1950369 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241408 NZ_CP095121:1945792-1945894 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241408 NZ_CP095121:c1945901-1945756 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References