Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4406002..4406539 Replicon chromosome
Accession NC_012962
Organism Photorhabdus asymbiotica

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAU_RS18815 Protein ID WP_041382452.1
Coordinates 4406002..4406280 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAU_RS18820 Protein ID WP_015835878.1
Coordinates 4406267..4406539 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAU_RS18795 4401005..4401529 + 525 WP_081461619.1 type VI secretion system tube protein Hcp -
PAU_RS18800 4401671..4402666 + 996 WP_015835874.1 hypothetical protein -
PAU_RS18805 4403251..4404222 - 972 WP_015835875.1 Rpn family recombination-promoting nuclease/putative transposase -
PAU_RS18810 4404711..4405061 - 351 WP_121302650.1 hypothetical protein -
PAU_RS24835 4405715..4405867 + 153 WP_015835877.1 S-type pyocin domain-containing protein -
PAU_RS18815 4406002..4406280 - 279 WP_041382452.1 type II toxin-antitoxin system YafQ family toxin Toxin
PAU_RS18820 4406267..4406539 - 273 WP_015835878.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PAU_RS18825 4406762..4409386 - 2625 WP_015835879.1 type VI secretion system ATPase TssH -
PAU_RS18830 4409439..4410530 - 1092 WP_015835880.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-65)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10813.84 Da        Isoelectric Point: 9.8190

>T24108 WP_041382452.1 NC_012962:c4406280-4406002 [Photorhabdus asymbiotica]
MLKIRQKAQFKKDLKKAILDRKRNTELLKTLINGLIVTGTVPETFKPHQLKGNWKPCMECHIQPDFLLIWDVDWEKQELI
LIRCGSHSELFG

Download         Length: 279 bp

>T24108 NC_012962:c4406280-4406002 [Photorhabdus asymbiotica]
ATGCTGAAGATTAGACAGAAAGCGCAATTTAAAAAGGATTTAAAAAAAGCGATTCTGGATAGAAAGAGGAACACGGAACT
ACTTAAAACACTCATTAACGGGCTAATTGTTACGGGTACTGTACCGGAGACTTTTAAGCCGCATCAATTAAAAGGAAATT
GGAAACCGTGTATGGAATGCCATATACAACCAGATTTTTTGTTGATATGGGATGTTGATTGGGAAAAACAGGAACTAATC
TTAATCCGATGTGGGTCTCATTCTGAATTATTTGGTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9804.20 Da        Isoelectric Point: 4.3449

>AT24108 WP_015835878.1 NC_012962:c4406539-4406267 [Photorhabdus asymbiotica]
MATIKAEIVRARVEPKLKEDAENVLSALGISLSDAIRIFLNQVSLRQEFPIELKVPNRTTLKTIAAPVTDEVFTSADELF
SSVCGGDAED

Download         Length: 273 bp

>AT24108 NC_012962:c4406539-4406267 [Photorhabdus asymbiotica]
ATGGCAACTATAAAAGCTGAAATTGTCAGAGCAAGAGTTGAACCCAAGTTGAAAGAAGATGCGGAAAATGTGTTATCCGC
GTTGGGAATAAGTCTATCTGATGCTATTAGGATATTTTTAAATCAGGTTTCATTAAGGCAGGAATTTCCTATCGAATTAA
AGGTACCTAACAGGACAACCCTAAAAACTATTGCTGCACCGGTAACTGATGAGGTATTCACTTCAGCAGATGAATTATTT
TCTAGTGTGTGTGGTGGTGATGCTGAAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References