Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1624837..1625434 Replicon chromosome
Accession NC_012962
Organism Photorhabdus asymbiotica

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAU_RS06995 Protein ID WP_041381701.1
Coordinates 1624837..1625148 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAU_RS07000 Protein ID WP_015833577.1
Coordinates 1625135..1625434 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAU_RS06970 1620865..1621797 + 933 WP_015833571.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase -
PAU_RS06975 1621878..1622963 + 1086 WP_015833572.1 chorismate synthase -
PAU_RS06980 1623051..1623851 + 801 WP_015833573.1 sulfite exporter TauE/SafE family protein -
PAU_RS06985 1623875..1624426 + 552 WP_015833574.1 elongation factor P hydroxylase -
PAU_RS06990 1624448..1624726 + 279 WP_015833575.1 YfcL family protein -
PAU_RS06995 1624837..1625148 - 312 WP_041381701.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
PAU_RS07000 1625135..1625434 - 300 WP_015833577.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PAU_RS07005 1625538..1627607 - 2070 WP_015833578.1 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC -
PAU_RS07010 1627777..1628388 - 612 WP_041381703.1 LysE family translocator -
PAU_RS07015 1628603..1629061 + 459 WP_015833580.1 Lrp/AsnC family transcriptional regulator -
PAU_RS07020 1629676..1630179 - 504 WP_015833581.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-55)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11738.43 Da        Isoelectric Point: 8.4950

>T24098 WP_041381701.1 NC_012962:c1625148-1624837 [Photorhabdus asymbiotica]
VLTLEWRETARADLLTIIDYISDDNPHAAQQLKNAIENKVATLPERPQLYRLGRIPGTREMVVQSNYVVVYAETTHTIVI
LRVLHTSQQWPPSSEIKATKSKT

Download         Length: 312 bp

>T24098 NC_012962:c1625148-1624837 [Photorhabdus asymbiotica]
GTGCTAACTCTTGAATGGAGGGAAACAGCCAGAGCTGACTTGTTGACAATTATTGATTACATATCTGACGATAATCCCCA
TGCAGCTCAACAGTTAAAAAACGCAATAGAGAATAAGGTGGCAACACTACCAGAGCGCCCGCAACTTTACCGACTAGGCC
GCATTCCCGGTACGCGGGAAATGGTTGTTCAATCCAACTATGTAGTAGTGTACGCCGAAACAACCCACACGATAGTTATC
CTACGGGTACTACACACCTCACAACAATGGCCACCATCAAGCGAGATAAAAGCAACGAAAAGCAAAACATAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10968.43 Da        Isoelectric Point: 5.0992

>AT24098 WP_015833577.1 NC_012962:c1625434-1625135 [Photorhabdus asymbiotica]
MAAQTSMLHVRVDDKLKADATKTLANLGLTVSDAVRILLTRVARDGALPAGFTADTETYDAWFFAKVQEALDDTRQPVPH
QQVMDEAQELIERKLRANS

Download         Length: 300 bp

>AT24098 NC_012962:c1625434-1625135 [Photorhabdus asymbiotica]
ATGGCAGCTCAAACATCAATGCTGCACGTTCGTGTAGACGATAAACTCAAAGCCGATGCAACAAAAACACTCGCTAATTT
AGGTCTAACCGTATCGGATGCTGTACGCATCCTGCTAACCCGTGTTGCCAGAGATGGTGCGTTACCCGCTGGTTTCACCG
CTGATACGGAAACTTACGATGCTTGGTTTTTCGCTAAAGTGCAAGAAGCACTCGACGATACGCGCCAACCTGTCCCACAT
CAGCAAGTAATGGATGAAGCCCAAGAATTAATTGAAAGGAAACTTCGTGCTAACTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References