Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1384075..1384738 Replicon chromosome
Accession NC_012962
Organism Photorhabdus asymbiotica

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PAU_RS05915 Protein ID WP_015833355.1
Coordinates 1384322..1384738 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag PAU_RS05910 Protein ID WP_015833354.1
Coordinates 1384075..1384341 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAU_RS05880 1379494..1379769 + 276 WP_041381656.1 hypothetical protein -
PAU_RS05885 1380120..1380470 + 351 WP_015833348.1 hypothetical protein -
PAU_RS22245 1380460..1380753 + 294 WP_015833349.1 hypothetical protein -
PAU_RS05895 1380964..1381878 + 915 WP_015833351.1 DMT family transporter -
PAU_RS05900 1382287..1382892 - 606 WP_015833352.1 HD domain-containing protein -
PAU_RS05905 1382903..1383898 - 996 WP_015833353.1 tRNA-modifying protein YgfZ -
PAU_RS05910 1384075..1384341 + 267 WP_015833354.1 FAD assembly factor SdhE Antitoxin
PAU_RS05915 1384322..1384738 + 417 WP_015833355.1 protein YgfX Toxin
PAU_RS05920 1384760..1385278 - 519 WP_041382730.1 flavodoxin FldB -
PAU_RS05925 1385407..1386297 + 891 WP_041382731.1 site-specific tyrosine recombinase XerD -
PAU_RS05930 1386322..1387023 + 702 WP_015833358.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PAU_RS05935 1387029..1388762 + 1734 WP_015833359.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16293.26 Da        Isoelectric Point: 9.6334

>T24097 WP_015833355.1 NC_012962:1384322-1384738 [Photorhabdus asymbiotica]
VVLWKCDLRVSWHTQLISTCAHGVIALIVLLAPWPADDAIFCIFWLPLVLLIIASWGRSQKNIRKSQGILVLLNDNKLQW
KKHEWQIIRQPWLCRYGLLITAQSFYNQKKIRLWIASDSMSQDEWRNINQLLLQYPDI

Download         Length: 417 bp

>T24097 NC_012962:1384322-1384738 [Photorhabdus asymbiotica]
GTGGTCCTGTGGAAATGTGATCTCAGGGTATCCTGGCATACCCAGCTAATTTCTACCTGTGCTCATGGTGTAATAGCACT
TATAGTACTACTTGCTCCGTGGCCGGCGGATGACGCTATTTTCTGCATTTTCTGGCTTCCTTTGGTCCTGTTGATTATTG
CCAGTTGGGGGCGTAGCCAGAAAAATATCCGTAAATCACAGGGGATTTTAGTTCTGCTCAATGATAATAAGTTGCAATGG
AAAAAACACGAATGGCAAATTATCCGACAGCCATGGCTGTGTCGCTATGGGCTATTAATTACCGCTCAATCTTTTTATAA
CCAGAAAAAAATCCGCCTATGGATAGCATCCGATAGTATGTCACAGGATGAATGGAGGAATATTAATCAACTGTTGTTGC
AATATCCTGATATCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10682.30 Da        Isoelectric Point: 4.8889

>AT24097 WP_015833354.1 NC_012962:1384075-1384341 [Photorhabdus asymbiotica]
MDIDNKARIHWACRRGMRELDISIMPFFKYEYDSLSDDDKRLFIRLLECADPDLFNWLMNHGCPEDEELFRMIKLIQNRN
KDRGPVEM

Download         Length: 267 bp

>AT24097 NC_012962:1384075-1384341 [Photorhabdus asymbiotica]
ATGGATATTGATAATAAAGCACGTATACATTGGGCATGTCGGCGTGGAATGCGTGAGCTGGATATTTCAATTATGCCGTT
TTTTAAGTATGAATATGACTCACTCAGTGATGATGATAAACGACTTTTTATTCGTTTACTCGAATGTGCTGATCCTGATC
TGTTTAACTGGCTAATGAATCATGGGTGTCCGGAAGATGAAGAGCTATTCCGCATGATTAAACTTATTCAGAATAGAAAT
AAAGATCGTGGTCCTGTGGAAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References