Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2381998..2382166 Replicon chromosome
Accession NZ_CP094999
Organism Klebsiella michiganensis strain fxq

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2382056..2382159 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2381998..2382166 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT472_RS11745 (MT472_11745) 2377125..2379185 + 2061 WP_042945478.1 oligopeptidase B -
MT472_RS11750 (MT472_11750) 2379192..2379851 - 660 WP_014229839.1 exodeoxyribonuclease X -
MT472_RS11755 (MT472_11755) 2379930..2380160 - 231 WP_004103351.1 DNA polymerase III subunit theta -
MT472_RS11760 (MT472_11760) 2380296..2380670 + 375 WP_014229838.1 CopC domain-containing protein YobA -
MT472_RS11765 (MT472_11765) 2380675..2381544 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
MT472_RS11770 (MT472_11770) 2381561..2381899 + 339 WP_004103344.1 YebY family protein -
- 2381998..2382166 - 169 - - Antitoxin
- 2382056..2382159 + 104 - - Toxin
MT472_RS11775 (MT472_11775) 2382284..2383243 - 960 WP_042945476.1 spore coat protein U domain-containing protein -
MT472_RS11780 (MT472_11780) 2383258..2385588 - 2331 WP_042945474.1 fimbria/pilus outer membrane usher protein -
MT472_RS11785 (MT472_11785) 2385591..2386355 - 765 WP_042945473.1 fimbria/pilus periplasmic chaperone -
MT472_RS11790 (MT472_11790) 2386374..2386892 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T240927 NZ_CP094999:2382056-2382159 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT240927 NZ_CP094999:c2382166-2381998 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References