Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 3345583..3346195 | Replicon | chromosome |
Accession | NZ_CP094998 | ||
Organism | Synechocystis sp. PCC 6803 substr. GT-T |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | MT986_RS15615 | Protein ID | WP_010874170.1 |
Coordinates | 3345833..3346195 (+) | Length | 121 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | MT986_RS15610 | Protein ID | WP_010874169.1 |
Coordinates | 3345583..3345843 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MT986_RS15595 (MT986_15595) | 3342669..3343421 | - | 753 | WP_223211306.1 | hypothetical protein | - |
MT986_RS15600 (MT986_15600) | 3343503..3344459 | - | 957 | WP_010874167.1 | quinolinate synthase NadA | - |
MT986_RS15605 (MT986_15605) | 3344552..3345298 | - | 747 | WP_010874168.1 | cytochrome c biogenesis protein CcdA | - |
MT986_RS15610 (MT986_15610) | 3345583..3345843 | + | 261 | WP_010874169.1 | hypothetical protein | Antitoxin |
MT986_RS15615 (MT986_15615) | 3345833..3346195 | + | 363 | WP_010874170.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
MT986_RS15620 (MT986_15620) | 3346332..3348938 | + | 2607 | WP_010874171.1 | bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase | - |
MT986_RS15625 (MT986_15625) | 3349168..3349995 | + | 828 | WP_010874172.1 | hypothetical protein | - |
MT986_RS15630 (MT986_15630) | 3350324..3350845 | + | 522 | WP_010874173.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 121 a.a. Molecular weight: 13679.59 Da Isoelectric Point: 8.2767
>T240920 WP_010874170.1 NZ_CP094998:3345833-3346195 [Synechocystis sp. PCC 6803]
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED
Download Length: 363 bp
>T240920 NZ_LT859959:c6104816-6104475 [Bradyrhizobium sp. ORS 285]
ATGGCAACGACACGCTTCGACGCGGCGGAATACCTGGCGGAGCCGGAGGCACAGGCCGAGTTTCTGGCGGCGGCGCTCGA
GGATGGCACCGCGGATGAGATCCGCGCCGCGATCAACACCATCGCGCGGGCGCGCGGCATGTCGGACCTCGCGAAGGCGA
CCGGCATCCGTCGCGAGCAGCTTTATCGGGCGCTGGGCGAGGACGGGAATCCGGAGTTTGCCACCATCCTGACCGTGCTC
CGTGCGCTCGGGGTGAAGCTGACGTCGGCGCCGGCGAAGGGGGCGTCAAAGGCGGCTCCGAAGCGGAAGACGGCGAAGAA
GGTTGGGCGGCGCGCTGCGTAA
ATGGCAACGACACGCTTCGACGCGGCGGAATACCTGGCGGAGCCGGAGGCACAGGCCGAGTTTCTGGCGGCGGCGCTCGA
GGATGGCACCGCGGATGAGATCCGCGCCGCGATCAACACCATCGCGCGGGCGCGCGGCATGTCGGACCTCGCGAAGGCGA
CCGGCATCCGTCGCGAGCAGCTTTATCGGGCGCTGGGCGAGGACGGGAATCCGGAGTTTGCCACCATCCTGACCGTGCTC
CGTGCGCTCGGGGTGAAGCTGACGTCGGCGCCGGCGAAGGGGGCGTCAAAGGCGGCTCCGAAGCGGAAGACGGCGAAGAA
GGTTGGGCGGCGCGCTGCGTAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9909.29 Da Isoelectric Point: 4.3705
>AT240920 WP_010874169.1 NZ_CP094998:3345583-3345843 [Synechocystis sp. PCC 6803]
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE
Download Length: 261 bp
>AT240920 NZ_LT859959:c6105113-6104820 [Bradyrhizobium sp. ORS 285]
ATGGTCGAAATCCGGCAAACGGCCGAGTTCAAGGCGTGGCTGCTCGGCCTGCGCGATCTGAAGGCAAAAGCCAGGATCGC
CGCGCGGATCGAGCGGGCCGCGAATGGCAATCTCGGCGACAGCAAGCCGGTCGGCGAGGGCGTCTCCGAGATGCGGATCG
ATTACGGCCCGGGCTACCGGATCTACTATCGGCAGCGTGGAGACGTCCTGGTCATCCTGCTCTGTGGTGGCGACAAGAGC
ACGCAACAGTCGGACATCCGGCGCGCCCAGGCACTGGCGAAGAGAGAGGCATAG
ATGGTCGAAATCCGGCAAACGGCCGAGTTCAAGGCGTGGCTGCTCGGCCTGCGCGATCTGAAGGCAAAAGCCAGGATCGC
CGCGCGGATCGAGCGGGCCGCGAATGGCAATCTCGGCGACAGCAAGCCGGTCGGCGAGGGCGTCTCCGAGATGCGGATCG
ATTACGGCCCGGGCTACCGGATCTACTATCGGCAGCGTGGAGACGTCCTGGTCATCCTGCTCTGTGGTGGCGACAAGAGC
ACGCAACAGTCGGACATCCGGCGCGCCCAGGCACTGGCGAAGAGAGAGGCATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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