Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1658887..1659529 Replicon chromosome
Accession NZ_CP094998
Organism Synechocystis sp. PCC 6803 substr. GT-T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MT986_RS07855 Protein ID WP_010872706.1
Coordinates 1659095..1659529 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MT986_RS07850 Protein ID WP_010872705.1
Coordinates 1658887..1659105 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT986_RS07835 (MT986_07835) 1654107..1654526 - 420 WP_231848060.1 heterocyst frequency control protein PatD -
MT986_RS07840 (MT986_07840) 1654861..1657143 + 2283 WP_010872703.1 RelA/SpoT family protein -
MT986_RS07845 (MT986_07845) 1657329..1658606 - 1278 WP_010872704.1 adenosylhomocysteinase -
MT986_RS07850 (MT986_07850) 1658887..1659105 + 219 WP_010872705.1 hypothetical protein Antitoxin
MT986_RS07855 (MT986_07855) 1659095..1659529 + 435 WP_010872706.1 putative toxin-antitoxin system toxin component, PIN family Toxin
MT986_RS07860 (MT986_07860) 1659557..1660441 - 885 WP_010872707.1 transglutaminase family protein -
MT986_RS07865 (MT986_07865) 1660540..1661103 - 564 WP_010872708.1 Uma2 family endonuclease -
MT986_RS07870 (MT986_07870) 1661124..1662320 - 1197 WP_041425818.1 glycosyltransferase family 1 protein -
MT986_RS07875 (MT986_07875) 1662372..1663451 - 1080 WP_230401109.1 hybrid sensor histidine kinase/response regulator -
MT986_RS07880 (MT986_07880) 1663425..1663568 + 144 WP_223211387.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16459.94 Da        Isoelectric Point: 4.4099

>T240916 WP_010872706.1 NZ_CP094998:1659095-1659529 [Synechocystis sp. PCC 6803]
MNNEVIRVVIDTNIWISFLIGKTLQGLNQAIIDNQVVILFSDTLFTELMEVLHHPKFKKYFSGTAIQNLIALLNEKVELV
EVNLHFDSYRDKKDNFLLDLAVSGNANYLVTGDSDLLTLNPFDNVEIISYQHFQAIILAMMDNQ

Download         Length: 435 bp

>T240916 NZ_LT855380:2046190-2046471 [Pseudomonas viridiflava]
ATGTTGCCCATTGTCTGGCTGCAAGCTGCTGTAAATGACCTTTCTTCAATCATCCTCTACATCTCCAATGAAAACCCCTC
TGCCGCTCGTCGCCTAAAATCACGTCTTCAGGCTGCGCCTTTACCATTAGTTGAACATCCTTATCTTTTTCCTCTGGGGC
GGGTTTCCGGTACGCGCGAACTCGTCGCGCATCCCAATTACATCATCGTTTACCGCATTGCCTCAGATCGAGTGGAGATC
GTGAACGTCTTGCATTCAAGGCAGACCTATCCGTTGACATGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8400.43 Da        Isoelectric Point: 4.2583

>AT240916 WP_010872705.1 NZ_CP094998:1658887-1659105 [Synechocystis sp. PCC 6803]
MHSLSSLEFPELKSVIAQCNLEEKLELLELLEKDTFGTRFNKFLNSVKTDELTLEDITQEVESVRQANYHEQ

Download         Length: 219 bp

>AT240916 NZ_LT855380:2045996-2046190 [Pseudomonas viridiflava]
ATGAGCACTACACTTTCCCCCATCGTTTCCGAATTTGATACGCAAGAGCAAGCTGATAGCTACGATCTCTGGTTTCGCGC
CAAGGTGGAAGCTTCGTTGGCCGAACCTGGACGTGCAGTGCCTCACGATGAAGTCATGGCGCGCATGGACGCGATCATTG
AGGCTGCTGAGGCCAGGCAGAGATTGGGTAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References