Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 545029..545588 Replicon chromosome
Accession NZ_CP094998
Organism Synechocystis sp. PCC 6803 substr. GT-T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MT986_RS02550 Protein ID WP_010871694.1
Coordinates 545250..545588 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MT986_RS02545 Protein ID WP_010871693.1
Coordinates 545029..545253 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT986_RS02525 (MT986_02525) 540863..542065 + 1203 WP_010871689.1 class I SAM-dependent methyltransferase -
MT986_RS02530 (MT986_02530) 542105..542596 - 492 WP_010871690.1 hypothetical protein -
MT986_RS02535 (MT986_02535) 542803..543342 + 540 WP_010871691.1 TerD family protein -
MT986_RS02540 (MT986_02540) 543468..544871 - 1404 WP_010871692.1 glutamate decarboxylase -
MT986_RS02545 (MT986_02545) 545029..545253 + 225 WP_010871693.1 DUF433 domain-containing protein Antitoxin
MT986_RS02550 (MT986_02550) 545250..545588 + 339 WP_010871694.1 DUF5615 family PIN-like protein Toxin
MT986_RS02555 (MT986_02555) 545591..546556 - 966 WP_010871695.1 carbon-nitrogen hydrolase family protein -
MT986_RS02560 (MT986_02560) 546553..547365 - 813 WP_014407074.1 urease accessory protein UreD -
MT986_RS02565 (MT986_02565) 547425..547874 - 450 WP_010871697.1 photosystem II protein PsbQ -
MT986_RS02570 (MT986_02570) 548236..549132 + 897 WP_010871698.1 prohibitin family protein -
MT986_RS02575 (MT986_02575) 549129..549701 - 573 WP_010871699.1 gamma carbonic anhydrase family protein -
MT986_RS02580 (MT986_02580) 549994..550329 + 336 WP_010871700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12464.32 Da        Isoelectric Point: 4.2931

>T240915 WP_010871694.1 NZ_CP094998:545250-545588 [Synechocystis sp. PCC 6803]
MNIWVDAQLPPTLADWLSSNFDLEASALRDLGLRDARDIEIFDAARVANSVIMTKDSDFVDLVCRLGIPPQIIWLTCGNV
TNRNLRRILSSTLPQALEKLQAGEIIIEISNS

Download         Length: 339 bp

>T240915 NZ_LT855380:c1319466-1319284 [Pseudomonas viridiflava]
ATGCGAAGCAGGGAAATGATAAGAACGATTGAGGATGATGGATGGTATCTCGTGGCGACCAAAGGTAGTCACCATCAATA
CAAGCACTCGTCAAAGCCTGGAAGGGTAACGATCAAGCACCCGGATTCCGATATACCGATCAAAACGATGAATAGCATAT
TGAAGCAAGCGGGATTGAAATAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.51 Da        Isoelectric Point: 4.6320

>AT240915 WP_010871693.1 NZ_CP094998:545029-545253 [Synechocystis sp. PCC 6803]
MNSLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLAENVSTSEILEDFPDLEMADIQACLVFAARRTDFSRLTA

Download         Length: 225 bp

>AT240915 NZ_LT855380:c1319178-1318768 [Pseudomonas viridiflava]
ATGAAATTCACCGTCGTTCTGCATAAAGACGCCGATTCAGACTATGGAGTAACTGTTCCGGACGTGCCTGGTTGCTTTTC
GGCAGGCAGCTCGGTATCGGAAGCACTGGAAAGTGTGAAGGAGGCGTTATCGCTGCACTTTGAAGGTCTGGTGGCCGATG
GCGCACCACTCCCCAATGCGCAAGCCATTGATATTCATATGGCCAATCCCGACTACGAAGACGGTATCTGGGCGGTGGTC
GAGTTCGACGTGACGCCTTATTTTGGCAAGTCAGTACGATTCAACGCGACACTTCCGGAACACCTGCTGGCCAAAATTGA
TGAGCGCGTCAAAACCGATCATCGATACGCCTCACGCTCTGGCTTTTTGGCCGCTGCGGCATTGAACGAGCTGCATACTG
AGTACCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References