Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 5538593..5539137 Replicon chromosome
Accession NZ_CP094997
Organism Dyadobacter chenwenxiniae strain LJ419

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MUK70_RS23715 Protein ID WP_234658739.1
Coordinates 5538593..5538904 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MUK70_RS23720 Protein ID WP_234658738.1
Coordinates 5538904..5539137 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUK70_RS23690 (MUK70_23690) 5534114..5534371 - 258 WP_234658744.1 type II toxin-antitoxin system RelE/ParE family toxin -
MUK70_RS23695 (MUK70_23695) 5534373..5534570 - 198 WP_234658742.1 hypothetical protein -
MUK70_RS23700 (MUK70_23700) 5534604..5535314 - 711 WP_234608738.1 ABC transporter ATP-binding protein -
MUK70_RS23705 (MUK70_23705) 5535352..5535804 - 453 WP_234658741.1 hypothetical protein -
MUK70_RS23710 (MUK70_23710) 5535841..5538504 - 2664 WP_234658740.1 hypothetical protein -
MUK70_RS23715 (MUK70_23715) 5538593..5538904 - 312 WP_234658739.1 DUF5615 family PIN-like protein Toxin
MUK70_RS23720 (MUK70_23720) 5538904..5539137 - 234 WP_234658738.1 DUF433 domain-containing protein Antitoxin
MUK70_RS23725 (MUK70_23725) 5539315..5540829 + 1515 WP_234608734.1 F0F1 ATP synthase subunit beta -
MUK70_RS23730 (MUK70_23730) 5540930..5541172 + 243 WP_234608733.1 ATP synthase F1 subunit epsilon -
MUK70_RS23735 (MUK70_23735) 5541244..5541927 - 684 WP_234658737.1 hypothetical protein -
MUK70_RS23740 (MUK70_23740) 5541942..5542673 - 732 WP_234658736.1 intradiol ring-cleavage dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(2-77)

Antitoxin

Protein of unknown function DUF433

(9-65)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11979.01 Da        Isoelectric Point: 7.5449

>T240913 WP_234658739.1 NZ_CP094997:c5538904-5538593 [Dyadobacter chenwenxiniae]
MIILDAHIPPSLALWIASHYNIECYSARFLNLCAAEDWEIFTLAKERNAIVITKDDDFVSLLNIHGCPPKVIWLTCGNTS
KERLREFCLKNCCKRWHCWNKPT

Download         Length: 312 bp

>T240913 NZ_LT855380:445402-445728 [Pseudomonas viridiflava]
GTGAAGCAGCACGGATTCAATCGCGCAGATATCGTCCGCATCAGCCTCAATCCAACCGCTGGCCGAGAACAGCAGCGCGA
TTTTCGTCCCGCGTTGGTGCTGACACCAGCAGCGTATAACGTCACCGGCCTTGCGATCGTTGCGCCTATCATACAGGGCG
GTGATTTTGCGCGTTATTCGGGGTTCGCTGTTCCTTTGGGTGGGGCGGGAGTCCCAAACAAAAGCCCCCGGAGACTCACG
TCGCCGGGGGCTTTTGATGACCGCAGGAGAATTACAGACCGGCAGCAGCGCGCAGGGCGTCGGCGCGGTCGGTTTTTTCC
CAAGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8571.05 Da        Isoelectric Point: 4.6652

>AT240913 WP_234658738.1 NZ_CP094997:c5539137-5538904 [Dyadobacter chenwenxiniae]
MNKQLLERITFNPNLCGGKPCIRNMRIRVTDVIELLANGLTAEQIVTEELPDLEPEDITACLLYAAIKLNHPVLQAA

Download         Length: 234 bp

>AT240913 NZ_LT855380:445151-445405 [Pseudomonas viridiflava]
ATGGAAGTCAAAATTCAGCAGTGGGGCAATAGCGCAGCAATCAGATTGCCAGCCAATGTGCTCAAGCAGATGAGCCTGGT
CATCGGTGATGTGCTGGTGCTGGATGTTTCCAGCGAAGTGATGACGCTCAAGCCTGCCAAGGCCAGACTGCATTACCAAT
TGGCCGACCTTATGGCCCAATGTGATTTGAATGCGTCCGAGCCAGAGGAGTTGGCTGGTTGGAACGCCATGCAACCCATA
GGGCGTGAAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References