Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5293638..5294212 Replicon chromosome
Accession NZ_CP094997
Organism Dyadobacter chenwenxiniae strain LJ419

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MUK70_RS22600 Protein ID WP_234655246.1
Coordinates 5293829..5294212 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MUK70_RS22595 Protein ID WP_234655245.1
Coordinates 5293638..5293832 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUK70_RS22580 (MUK70_22580) 5288853..5290607 - 1755 WP_234655243.1 response regulator -
MUK70_RS22585 (MUK70_22585) 5290745..5292142 - 1398 WP_234655244.1 dihydrolipoyl dehydrogenase -
MUK70_RS22590 (MUK70_22590) 5292445..5293519 + 1075 WP_234603305.1 peptide chain release factor 2 -
MUK70_RS22595 (MUK70_22595) 5293638..5293832 + 195 WP_234655245.1 DUF2281 domain-containing protein Antitoxin
MUK70_RS22600 (MUK70_22600) 5293829..5294212 + 384 WP_234655246.1 type II toxin-antitoxin system VapC family toxin Toxin
MUK70_RS22605 (MUK70_22605) 5294206..5295000 + 795 WP_234655247.1 alpha/beta hydrolase -
MUK70_RS22610 (MUK70_22610) 5295023..5296312 + 1290 WP_234655248.1 MFS transporter -
MUK70_RS22615 (MUK70_22615) 5296393..5296827 + 435 WP_234655249.1 DoxX family protein -
MUK70_RS22620 (MUK70_22620) 5296832..5297707 - 876 WP_234603312.1 AraC family transcriptional regulator -
MUK70_RS22625 (MUK70_22625) 5297865..5298089 - 225 WP_234655250.1 hypothetical protein -
MUK70_RS22630 (MUK70_22630) 5298228..5299199 - 972 WP_234655388.1 dihydrodipicolinate synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(4-125)

Antitoxin

Domain of unknown function DUF2281

(2-62)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14646.93 Da        Isoelectric Point: 4.4988

>T240912 WP_234655246.1 NZ_CP094997:5293829-5294212 [Dyadobacter chenwenxiniae]
MNILLDTHALIWFLEGDANLSENALEAIENKDNKKYVSIASLWEIAIKISLGKLSLQNSLDLFLEELVESDIHILPISIK
HILLLSEFDFFHKDPFDRLIIAQGITEHFVIISKDSNFLLYSVELHW

Download         Length: 384 bp

>T240912 NZ_LT855377:c86896-86498 [Salmonella enterica subsp. enterica serovar Typhimurium]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7452.69 Da        Isoelectric Point: 4.7247

>AT240912 WP_234655245.1 NZ_CP094997:5293638-5293832 [Dyadobacter chenwenxiniae]
MKKVSVLPENLKEEVSDYVDFLISKYLPGESVNKKPLKFGMMKGTFKMSPDFDEPLDDFKEYMP

Download         Length: 195 bp

>AT240912 NZ_LT855377:c87123-86896 [Salmonella enterica subsp. enterica serovar Typhimurium]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References