Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4946616..4947640 Replicon chromosome
Accession NZ_CP094997
Organism Dyadobacter chenwenxiniae strain LJ419

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag MUK70_RS21090 Protein ID WP_255716338.1
Coordinates 4947062..4947640 (+) Length 193 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag MUK70_RS21085 Protein ID WP_234655003.1
Coordinates 4946616..4947065 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUK70_RS21070 (MUK70_21070) 4943227..4945035 + 1809 WP_234655001.1 glycoside hydrolase family 15 protein -
MUK70_RS21075 (MUK70_21075) 4945145..4945918 + 774 WP_234602795.1 NYN domain-containing protein -
MUK70_RS21080 (MUK70_21080) 4946013..4946513 + 501 WP_234655002.1 VanZ family protein -
MUK70_RS21085 (MUK70_21085) 4946616..4947065 + 450 WP_234655003.1 helix-turn-helix domain-containing protein Antitoxin
MUK70_RS21090 (MUK70_21090) 4947062..4947640 + 579 WP_255716338.1 PIN domain-containing protein Toxin
MUK70_RS21095 (MUK70_21095) 4947739..4947981 - 243 WP_234655005.1 hypothetical protein -
MUK70_RS21100 (MUK70_21100) 4948407..4949123 + 717 WP_234655006.1 three-Cys-motif partner protein TcmP -
MUK70_RS21105 (MUK70_21105) 4949141..4949506 + 366 WP_234655007.1 hypothetical protein -
MUK70_RS21110 (MUK70_21110) 4949508..4950233 + 726 WP_234655008.1 phage Gp37/Gp68 family protein -
MUK70_RS21115 (MUK70_21115) 4950578..4950919 + 342 WP_256464080.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(10-116)

Antitoxin

Helix-turn-helix domain, group 17

(78-122)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21720.14 Da        Isoelectric Point: 5.9987

>T240911 WP_255716338.1 NZ_CP094997:4947062-4947640 [Dyadobacter chenwenxiniae]
MIHSARFVAILDACVLYPAPIRDLLLYLADAELYTPKWTDKIHEEWTQSLLKKRSDISSEQLRKTIAAMHNAFPDANVLN
YQSLMKSLELPDPNDAHVLAAAVRCNADVLVTANIKDFPKEYLQQFDIEPQHPDVFISNLIELNPDNTLKAFENQVGNLR
KPSLTACAVLDKLEKVGLIKTSSMFLRLMQSL

Download         Length: 579 bp

>T240911 NZ_LT855377:20315-20620 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16987.60 Da        Isoelectric Point: 9.6528

>AT240911 WP_234655003.1 NZ_CP094997:4946616-4947065 [Dyadobacter chenwenxiniae]
METVLERPTKREQKMASESVTNFTSAISRRKSDTVNIRIQESEELFTIPRRALEFLSHILSIMAEGKAISVFPSESELST
QQAADILHVSRPHIVKLLEQGVIPFKKAGSHRRILLEDLMKHAAMQKETTRKSLKFLVEQAQDLNLGYE

Download         Length: 450 bp

>AT240911 NZ_LT855377:20095-20313 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References