Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1946064..1946209 | Replicon | chromosome |
| Accession | NZ_CP094991 | ||
| Organism | Klebsiella pneumoniae strain SCPM-O-B-8919 (12PKP/19c) | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1946100..1946202 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1946064..1946209 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KF986_RS09320 (KF986_009320) | 1941194..1943254 | + | 2061 | WP_064145333.1 | oligopeptidase B | - |
| KF986_RS09325 (KF986_009325) | 1943258..1943917 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KF986_RS09330 (KF986_009330) | 1943996..1944226 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KF986_RS09335 (KF986_009335) | 1944339..1944713 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KF986_RS09340 (KF986_009340) | 1944717..1945586 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| KF986_RS09345 (KF986_009345) | 1945603..1945941 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1946064..1946209 | - | 146 | - | - | Antitoxin |
| - | 1946100..1946202 | + | 103 | - | - | Toxin |
| KF986_RS09350 (KF986_009350) | 1946578..1946721 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| KF986_RS09355 (KF986_009355) | 1946826..1947794 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| KF986_RS09360 (KF986_009360) | 1947951..1948604 | + | 654 | WP_064145335.1 | protein-serine/threonine phosphatase | - |
| KF986_RS09365 (KF986_009365) | 1948601..1948792 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KF986_RS09370 (KF986_009370) | 1948890..1949129 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KF986_RS09375 (KF986_009375) | 1949245..1950678 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T240891 NZ_CP094991:1946100-1946202 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT240891 NZ_CP094991:c1946209-1946064 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT