Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2652694..2652928 | Replicon | chromosome |
| Accession | NZ_CP094987 | ||
| Organism | Shigella flexneri strain 3160_NCHU22 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2652695..2652798 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2652694..2652928 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MT485_RS13360 | 2648140..2648607 | - | 468 | Protein_2597 | DNA-binding transcriptional regulator PgrR | - |
| MT485_RS13365 | 2648671..2648981 | + | 311 | Protein_2598 | transposase | - |
| MT485_RS13370 | 2649024..2650219 | - | 1196 | Protein_2599 | IS3 family transposase | - |
| MT485_RS13375 | 2650274..2651122 | + | 849 | Protein_2600 | IS3-like element IS600 family transposase | - |
| MT485_RS13380 | 2651239..2651520 | + | 282 | WP_005127484.1 | excisionase | - |
| MT485_RS13385 | 2651486..2652563 | + | 1078 | Protein_2602 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2652694..2652928 | + | 235 | - | - | Antitoxin |
| - | 2652695..2652798 | - | 104 | - | - | Toxin |
| MT485_RS13390 | 2652956..2653297 | - | 342 | WP_000976476.1 | YebY family protein | - |
| MT485_RS13395 | 2653310..2654182 | - | 873 | Protein_2604 | copper homeostasis membrane protein CopD | - |
| MT485_RS13400 | 2654186..2654560 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| MT485_RS13405 | 2654699..2654929 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| MT485_RS13410 | 2655031..2655687 | + | 657 | Protein_2607 | carbon-nitrogen hydrolase family protein YobB | - |
| MT485_RS13415 | 2655711..2656373 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2648671..2658430 | 9759 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T240864 NZ_CP094987:c2652798-2652695 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT240864 NZ_CP094987:2652694-2652928 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
