240856

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 5891498..5892066 Replicon chromosome
Accession NZ_CP094975
Organism Pseudomonas sp. PIA16

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L9B60_RS26790 Protein ID WP_249673987.1
Coordinates 5891770..5892066 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L9B60_RS26785 Protein ID WP_249673986.1
Coordinates 5891498..5891773 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L9B60_RS26765 5886561..5887454 + 894 WP_249673982.1 DMT family transporter -
L9B60_RS26770 5887445..5890069 - 2625 WP_249673983.1 EAL domain-containing protein -
L9B60_RS26775 5890182..5890520 - 339 WP_249673984.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
L9B60_RS26780 5890591..5891493 + 903 WP_249673985.1 LysR family transcriptional regulator -
L9B60_RS26785 5891498..5891773 - 276 WP_249673986.1 putative addiction module antidote protein Antitoxin
L9B60_RS26790 5891770..5892066 - 297 WP_249673987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L9B60_RS26795 5892180..5893001 - 822 WP_249673988.1 aldo/keto reductase -
L9B60_RS26800 5893053..5893952 - 900 WP_249673989.1 LysR family transcriptional regulator -
L9B60_RS26805 5894083..5894781 + 699 WP_249673990.1 CoA transferase subunit A -
L9B60_RS26810 5894811..5895467 + 657 WP_249673991.1 CoA transferase subunit B -
L9B60_RS26815 5895610..5897028 + 1419 WP_249673992.1 TIGR00366 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-91)

Antitoxin

Uncharacterized protein HI1420

(11-88)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10855.45 Da        Isoelectric Point: 10.0304

>T240856 WP_249673987.1 NZ_CP094975:c5892066-5891770 [Pseudomonas sp. PIA16]
MTTGAFDQWLRALKDYKARARITARLLSAQMGNFGNCQPVGEGISEMRIHTGPGYRVYYSRRGEVVYLLLCAGDKASQKL
DIRNAKALLSDIDRGAST

Download         Length: 297 bp

>T240856 NZ_LT838196:2736448-2736555 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9956.34 Da        Isoelectric Point: 5.0493

>AT240856 WP_249673986.1 NZ_CP094975:c5891773-5891498 [Pseudomonas sp. PIA16]
MTTLNTFEAANYLTDEATIAEFLTAALEDENPDVFLQALQEVAKSRGMSQVARDAGLNRESLYKALAPGAKPRYDTVFKV
IHALGIKLCAH

Download         Length: 276 bp

>AT240856 NZ_LT838196:c2736401-2736335 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References