Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4123142..4123779 Replicon chromosome
Accession NZ_CP094975
Organism Pseudomonas sp. PIA16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L9B60_RS18945 Protein ID WP_249672265.1
Coordinates 4123142..4123549 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag L9B60_RS18950 Protein ID WP_249672266.1
Coordinates 4123549..4123779 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L9B60_RS18930 4118363..4120072 + 1710 WP_249672262.1 single-stranded-DNA-specific exonuclease RecJ -
L9B60_RS18935 4120168..4121274 + 1107 WP_249672263.1 NADH:flavin oxidoreductase/NADH oxidase -
L9B60_RS18940 4121341..4122957 - 1617 WP_249672264.1 glucan biosynthesis protein D -
L9B60_RS18945 4123142..4123549 - 408 WP_249672265.1 type II toxin-antitoxin system VapC family toxin Toxin
L9B60_RS18950 4123549..4123779 - 231 WP_249672266.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
L9B60_RS18955 4124005..4125483 - 1479 WP_249672267.1 amino acid permease -
L9B60_RS18960 4125643..4127067 - 1425 WP_249672268.1 gamma-aminobutyraldehyde dehydrogenase -
L9B60_RS18965 4127092..4127901 - 810 WP_249672269.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15262.32 Da        Isoelectric Point: 7.3847

>T240854 WP_249672265.1 NZ_CP094975:c4123549-4123142 [Pseudomonas sp. PIA16]
MSVRYLLDTNICIYIAKHNPASVRERFQRHSASELAMSVVTLGELRFGAQKSQARERSLLAVNHLQSLIQVAELQPCVGE
HYGEIRAQLQASGQVIGNNDLWLAAHARSNDWILVSNNVREFERVQGLQVENWVP

Download         Length: 408 bp

>T240854 NZ_LT838196:2367423-2368745 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8710.72 Da        Isoelectric Point: 4.5859

>AT240854 WP_249672266.1 NZ_CP094975:c4123779-4123549 [Pseudomonas sp. PIA16]
MTFARVFQSGNSQAVRLPKEFRLDVDRVEIFRRGDEIVLREHPVNASAIFDALTQLPADFMEGGRDDSAPQERENF

Download         Length: 231 bp

>AT240854 NZ_LT838196:2367157-2367423 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References