Detailed information of TA system TA240851

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 2259183..2259699
• Replicon: chromosome
• Accession: NZ_CP094975
• Organism: Pseudomonas sp. PIA16

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L9B60_RS10090
• Protein ID: WP_093425407.1
• Coordinates: 2259183..2259470 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L9B60_RS10095
• Protein ID: WP_093425410.1
• Coordinates: 2259460..2259699 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L9B60_RS10080	2256598..2257341	-	744	WP_249678345.1	HNH endonuclease	-
L9B60_RS10085	2257347..2258516	-	1170	WP_249678346.1	AAA family ATPase	-
L9B60_RS10090	2259183..2259470	-	288	WP_093425407.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L9B60_RS10095	2259460..2259699	-	240	WP_093425410.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
L9B60_RS10100	2260758..2261420	+	663	WP_249678347.1	hypothetical protein	-
L9B60_RS10105	2262620..2262925	+	306	WP_249678348.1	hypothetical protein	-
L9B60_RS10110	2263218..2263427	+	210	WP_249678349.1	hypothetical protein	-
L9B60_RS10115	2263581..2264000	+	420	WP_249678350.1	PH domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11235.14 Da
• Isoelectric Point: 10.2588

>T240851 WP_093425407.1 NZ_CP094975:c2259470-2259183 [Pseudomonas sp. PIA16]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVNPRIEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
REREQVYRKAAERLS

Nucleotide

• Length: 288 bp

>T240851 NZ_LT838196:c1848278-1847913 [Escherichia coli]
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTACTGGACCAGCATTACAGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGCGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGCACTGGTACGAACTGACCAGCCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8978.31 Da
• Isoelectric Point: 4.7962

>AT240851 WP_093425410.1 NZ_CP094975:c2259699-2259460 [Pseudomonas sp. PIA16]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALVATVRERLANPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT240851 NZ_LT838196:c1848736-1848368 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGAGATGCGGATGCGTACCCTCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGAAATTAATGCTCACCAGTGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA