Detailed information of TA system TA240833

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): DhiAT/dnstrm_HI1420(antitoxin)
• Location: 1841765..1842519
• Replicon: chromosome
• Accession: NZ_CP094943
• Organism: Dickeya dadantii strain FZ06

Toxin (Protein)

• Gene name: dhiT
• Uniprot ID: -
• Locus tag: MUB29_RS08170
• Protein ID: WP_216282363.1
• Coordinates: 1841765..1842022 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: dhiA
• Uniprot ID: -
• Locus tag: MUB29_RS08175
• Protein ID: WP_216282364.1
• Coordinates: 1842031..1842519 (+)
• Length: 163 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUB29_RS08160	1838526..1840676	-	2151	WP_263065084.1	formate dehydrogenase subunit alpha	-
MUB29_RS08165	1840711..1841253	-	543	WP_013317225.1	4Fe-4S dicluster domain-containing protein	-
MUB29_RS08170	1841765..1842022	+	258	WP_216282363.1	DUF4160 domain-containing protein	Toxin
MUB29_RS08175	1842031..1842519	+	489	WP_216282364.1	DUF2442 domain-containing protein	Antitoxin
MUB29_RS08180	1842598..1843092	-	495	WP_263065085.1	hydrogenase maturation peptidase HycI	-
MUB29_RS08185	1843085..1843483	-	399	WP_263065086.1	formate hydrogenlyase maturation HycH family protein	-
MUB29_RS08190	1843480..1844271	-	792	WP_013317231.1	NADH-quinone oxidoreductase subunit B family protein	-
MUB29_RS08195	1844268..1844837	-	570	WP_263065087.1	hydrogenase 4 subunit H	-
MUB29_RS08200	1844848..1846575	-	1728	WP_263065088.1	hydrogenase large subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF4160 (9-73)

Antitoxin

• Protein of unknown function DUF2442 (4-71)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10003.61 Da
• Isoelectric Point: 7.1842

>T240833 WP_216282363.1 NZ_CP094943:1841765-1842022 [Dickeya dadantii]
MPEIDRLAGLIFYLYFYDDDRHHLPHVHVCYGDDELIIAIDTGVEIEGYLPNSKRKMAIKHINTHRQHLLEMWKLAVKGR
HPGKL

Nucleotide

• Length: 258 bp

>T240833 NZ_LT827011:c1981393-1981291 [Escherichia coli O127:H6]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 163 a.a.
• Molecular weight: 17967.54 Da
• Isoelectric Point: 6.8729

>AT240833 WP_216282364.1 NZ_CP094943:1842031-1842519 [Dickeya dadantii]
MHKIIDVDVTGDFTLRLTYEDGLICDVDLYQYAPDPVFSNASLFIKFGLLPDGALEWQPDIKISASDLRKKGVYVGHTLA
VRERRFADVISRAFYDAVIENRPEILQAALKTAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLE
EK

Nucleotide

• Length: 489 bp

>AT240833 NZ_LT827011:1981253-1981521 [Escherichia coli O127:H6]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT