Detailed information of TA system TA240830

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 739556..740234
• Replicon: chromosome
• Accession: NZ_CP094943
• Organism: Dickeya dadantii strain FZ06

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: MUB29_RS03420
• Protein ID: WP_216281604.1
• Coordinates: 739803..740234 (+)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: MUB29_RS03415
• Protein ID: WP_013316361.1
• Coordinates: 739556..739822 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUB29_RS03395	736016..736666	+	651	WP_038921713.1	LysE family translocator	-
MUB29_RS03400	736736..737344	-	609	WP_263064519.1	HD domain-containing protein	-
MUB29_RS03405	737553..738203	+	651	WP_263064520.1	hemolysin III family protein	-
MUB29_RS03410	738276..739256	-	981	WP_263064521.1	tRNA-modifying protein YgfZ	-
MUB29_RS03415	739556..739822	+	267	WP_013316361.1	FAD assembly factor SdhE	Antitoxin
MUB29_RS03420	739803..740234	+	432	WP_216281604.1	protein YgfX	Toxin
MUB29_RS03425	740331..740849	-	519	WP_216281605.1	flavodoxin FldB	-
MUB29_RS03430	740979..742304	-	1326	WP_216281606.1	MFS transporter	-
MUB29_RS03435	742567..743466	+	900	WP_216281608.1	site-specific tyrosine recombinase XerD	-
MUB29_RS03440	743556..744272	+	717	WP_226055610.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16794.50 Da
• Isoelectric Point: 10.2155

>T240830 WP_216281604.1 NZ_CP094943:739803-740234 [Dickeya dadantii]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVCSQRIIKTRQGEISLHGENQLHWQQR
DWQIVRRPWLMRNGVLLSLRAVDGKGHQRLWLASDSMGNEEWRLLRQLLQQHSLQGTESSHHH

Nucleotide

• Length: 432 bp

>T240830 NZ_LT827011:c1337514-1337407 [Escherichia coli O127:H6]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTTGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10476.98 Da
• Isoelectric Point: 5.5981

>AT240830 WP_013316361.1 NZ_CP094943:739556-739822 [Dickeya dadantii]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT240830 NZ_LT827011:1337562-1337628 [Escherichia coli O127:H6]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC