Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1981749..1981894 Replicon chromosome
Accession NZ_CP094940
Organism Klebsiella pneumoniae strain FK1979

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1981785..1981887 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1981749..1981894 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUB43_RS09570 1976879..1978939 + 2061 WP_004151449.1 oligopeptidase B -
MUB43_RS09575 1978943..1979602 - 660 WP_002911407.1 exodeoxyribonuclease X -
MUB43_RS09580 1979681..1979911 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MUB43_RS09585 1980024..1980398 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MUB43_RS09590 1980402..1981271 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MUB43_RS09595 1981288..1981626 + 339 WP_002911404.1 YebY family protein -
- 1981749..1981894 - 146 - - Antitoxin
- 1981785..1981887 + 103 - - Toxin
MUB43_RS09600 1982261..1982404 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MUB43_RS09605 1982509..1983477 - 969 WP_004151446.1 VirK/YbjX family protein -
MUB43_RS09610 1983634..1984287 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
MUB43_RS09615 1984284..1984475 - 192 WP_002911395.1 YebW family protein -
MUB43_RS09620 1984573..1984812 - 240 WP_002911393.1 YebV family protein -
MUB43_RS09625 1984928..1986361 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T240812 NZ_CP094940:1981785-1981887 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT240812 NZ_CP094940:c1981894-1981749 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References