Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 774343..774889 Replicon chromosome
Accession NZ_CP094929
Organism Sphaerochaeta associata strain GLS2T

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MUG09_RS03540 Protein ID WP_244773621.1
Coordinates 774611..774889 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MUG09_RS03535 Protein ID WP_244773620.1
Coordinates 774343..774618 (+) Length 92 a.a.

Genomic Context

MUG09_RS03525MUG09_RS03530MUG09_RS03535MUG09_RS03540MUG09_RS03545MUG09_RS03550MUG09_RS03565MUG09_RS03505MUG09_RS03510MUG09_RS03515MUG09_RS03520MUG09_RS03555MUG09_RS03560
Location: 773427..773786 (360 bp)
Type: Others
Protein ID: WP_244773618.1
Location: 773783..774091 (309 bp)
Type: Others
Protein ID: WP_244773619.1
Location: 774343..774618 (276 bp)
Type: Antitoxin
Protein ID: WP_244773620.1
Location: 774611..774889 (279 bp)
Type: Toxin
Protein ID: WP_244773621.1
Location: 775239..776003 (765 bp)
Type: Others
Protein ID: WP_244773622.1
Location: 775978..776895 (918 bp)
Type: Others
Protein ID: WP_244773624.1
Location: 779548..779709 (162 bp)
Type: Others
Protein ID: WP_244773627.1
Location: 769615..770268 (654 bp)
Type: Others
Protein ID: WP_244773613.1
Location: 770341..771138 (798 bp)
Type: Others
Protein ID: WP_244773616.1
Location: 771185..771922 (738 bp)
Type: Others
Protein ID: WP_280529404.1
Location: 772390..772983 (594 bp)
Type: Others
Protein ID: WP_244773617.1
Location: 777185..777619 (435 bp)
Type: Others
Protein ID: WP_244773625.1
Location: 779212..779616 (405 bp)
Type: Others
Protein ID: WP_244775357.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MUG09_RS03505 (MUG09_03505)769615..770268-654WP_244773613.1amino acid ABC transporter permease-
MUG09_RS03510 (MUG09_03510)770341..771138-798WP_244773616.1transporter substrate-binding domain-containing protein-
MUG09_RS03515 (MUG09_03515)771185..771922-738WP_280529404.1amino acid ABC transporter ATP-binding protein-
MUG09_RS03520 (MUG09_03520)772390..772983-594WP_244773617.1hypothetical protein-
MUG09_RS03525 (MUG09_03525)773427..773786+360WP_244773618.1type II toxin-antitoxin system RelE/ParE family toxin-
MUG09_RS03530 (MUG09_03530)773783..774091+309WP_244773619.1transcriptional regulator-
MUG09_RS03535 (MUG09_03535)774343..774618+276WP_244773620.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
MUG09_RS03540 (MUG09_03540)774611..774889+279WP_244773621.1type II toxin-antitoxin system YafQ family toxinToxin
MUG09_RS03545 (MUG09_03545)775239..776003+765WP_244773622.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein-
MUG09_RS03550 (MUG09_03550)775978..776895+918WP_244773624.1nucleotidyl transferase AbiEii/AbiGii toxin family protein-
MUG09_RS03555 (MUG09_03555)777185..777619-435WP_244773625.1nucleotidyltransferase substrate binding protein-
MUG09_RS03560 (MUG09_03560)779212..779616-405WP_244775357.1sugar phosphate nucleotidyltransferase-
MUG09_RS03565 (MUG09_03565)779548..779709+162WP_244773627.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10760.64 Da        Isoelectric Point: 9.1484

>T240804 WP_244773621.1 NZ_CP094929:774611-774889 [Sphaerochaeta associata]
MLKLEFTGQFKKDYKLAIKRGCNPSKLEQVITLLCNEQPLPEVYRDHALVNSRNYTGMRECHIQPDWLLVYKVVQQALIL
KLIRTGTHSDLF

Download         Length: 279 bp

>T240804 NZ_LT795502:1865277-1865528 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCCCTGGAGGAGACGGCTTATC
TACTGCGTTCCCCCGCTAATGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCTGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9957.37 Da        Isoelectric Point: 4.5049

>AT240804 WP_244773620.1 NZ_CP094929:774343-774618 [Sphaerochaeta associata]
MAGKADTSMTIRMNRDVKQQAQQIFSDLGMDMSTAINIFLRQAISFKGLPFEVALHTPNEVTLAAMDAAEHDKDMHGPFE
SVASLMDALDA

Download         Length: 276 bp

>AT240804 NZ_LT795502:1865525-1865779 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References