Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1913417..1913688 Replicon chromosome
Accession NC_012947
Organism Escherichia coli BL21-Gold(DE3)pLysS AG

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1913547..1913650 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1913417..1913688 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECBD_RS09315 1909973..1910635 - 663 WP_000944245.1 exodeoxyribonuclease X -
ECBD_RS09320 1910659..1911315 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
ECBD_RS09325 1911417..1911647 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ECBD_RS09330 1911786..1912160 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ECBD_RS09335 1912164..1913036 + 873 WP_000879293.1 copper homeostasis membrane protein CopD -
ECBD_RS09340 1913049..1913390 + 342 WP_000976472.1 YebY family protein -
- 1913417..1913688 - 272 - - Antitoxin
- 1913547..1913650 + 104 - - Toxin
ECBD_RS09350 1913785..1914441 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
ECBD_RS09355 1914442..1914633 - 192 WP_001296140.1 YebW family protein -
ECBD_RS09360 1914738..1914974 - 237 WP_001295499.1 DUF1480 family protein -
ECBD_RS09365 1915092..1916531 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T24076 NC_012947:1913547-1913650 [Escherichia coli 'BL21-Gold(DE3)pLysS AG']
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT24076 NC_012947:c1913688-1913417 [Escherichia coli 'BL21-Gold(DE3)pLysS AG']
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References