Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1459259..1459773 Replicon chromosome
Accession NZ_CP094844
Organism Ornithobacterium rhinotracheale strain A171

Toxin (Protein)


Gene name relE Uniprot ID I4A110
Locus tag MT993_RS06930 Protein ID WP_014791206.1
Coordinates 1459516..1459773 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID I4A109
Locus tag MT993_RS06925 Protein ID WP_014791205.1
Coordinates 1459259..1459513 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT993_RS06910 (MT993_06910) 1454455..1455582 + 1128 WP_014791202.1 imelysin family protein -
MT993_RS06915 (MT993_06915) 1455609..1456976 + 1368 WP_014791203.1 HTTM domain-containing protein -
MT993_RS06920 (MT993_06920) 1456957..1459188 + 2232 WP_014791204.1 TonB-dependent receptor -
MT993_RS06925 (MT993_06925) 1459259..1459513 + 255 WP_014791205.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MT993_RS06930 (MT993_06930) 1459516..1459773 + 258 WP_014791206.1 Txe/YoeB family addiction module toxin Toxin
MT993_RS06935 (MT993_06935) 1459829..1460122 - 294 WP_014791207.1 chaperone modulator CbpM -
MT993_RS06940 (MT993_06940) 1460128..1461054 - 927 WP_014791208.1 J domain-containing protein -
MT993_RS06945 (MT993_06945) 1461106..1461879 - 774 WP_014791209.1 nucleoside triphosphate pyrophosphohydrolase -
MT993_RS06950 (MT993_06950) 1461968..1462393 - 426 WP_014791210.1 DUF5606 domain-containing protein -
MT993_RS06955 (MT993_06955) 1462443..1463015 - 573 WP_014791211.1 peptide deformylase -
MT993_RS06960 (MT993_06960) 1463166..1463579 - 414 WP_155814511.1 Holliday junction resolvase RuvX -
MT993_RS06965 (MT993_06965) 1463594..1463887 - 294 WP_014791213.1 ATP-dependent Clp protease adaptor ClpS -
MT993_RS06970 (MT993_06970) 1463891..1464718 - 828 WP_014791214.1 50S ribosomal protein L11 methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10592.16 Da        Isoelectric Point: 8.4443

>T240646 WP_014791206.1 NZ_CP094844:1459516-1459773 [Ornithobacterium rhinotracheale]
MKYIFVDESWEDYLYWQKDDKRKLKRINALLKDISRTPFEGIGKPEPLKHKYSGFWSRRIDDEHCLIYRYEEDKILIAKC
RFHYD

Download         Length: 258 bp

>T240646 NZ_LT604072:c4464662-4464510 [Xanthomonas translucens pv. translucens DSM 18974]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9587.97 Da        Isoelectric Point: 6.3475

>AT240646 WP_014791205.1 NZ_CP094844:1459259-1459513 [Ornithobacterium rhinotracheale]
MLVTNISEFRKDLKSYLNKVAKNFETLIINRGKESAIVVLSLDEYNSLMATNYELSSRKNEQRLDAAIAKLKSGESFEKT
LIED

Download         Length: 255 bp

>AT240646 NZ_LT604072:c4464411-4464277 [Xanthomonas translucens pv. translucens DSM 18974]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I4A110

Antitoxin

Source ID Structure
AlphaFold DB I4A109

References