Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3967347..3968004 Replicon chromosome
Accession NZ_CP094841
Organism Enterobacter ludwigii strain Sb-9

Toxin (Protein)


Gene name cptA Uniprot ID G8LDB6
Locus tag MT488_RS19060 Protein ID WP_014171514.1
Coordinates 3967347..3967757 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag MT488_RS19065 Protein ID WP_003863437.1
Coordinates 3967738..3968004 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MT488_RS19040 (MT488_19040) 3963345..3965078 - 1734 WP_014171509.1 single-stranded-DNA-specific exonuclease RecJ -
MT488_RS19045 (MT488_19045) 3965084..3965797 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MT488_RS19050 (MT488_19050) 3965821..3966717 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
MT488_RS19055 (MT488_19055) 3966819..3967340 + 522 WP_014171513.1 flavodoxin FldB -
MT488_RS19060 (MT488_19060) 3967347..3967757 - 411 WP_014171514.1 protein YgfX Toxin
MT488_RS19065 (MT488_19065) 3967738..3968004 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
MT488_RS19070 (MT488_19070) 3968299..3969279 + 981 WP_020883730.1 tRNA-modifying protein YgfZ -
MT488_RS19075 (MT488_19075) 3969389..3970048 - 660 WP_014171517.1 hemolysin III family protein -
MT488_RS19080 (MT488_19080) 3970315..3971046 + 732 WP_040018863.1 MurR/RpiR family transcriptional regulator -
MT488_RS19085 (MT488_19085) 3971163..3972596 + 1434 WP_244047454.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16217.15 Da        Isoelectric Point: 11.5020

>T240642 WP_014171514.1 NZ_CP094841:c3967757-3967347 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGMPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

>T240642 NZ_LT604072:c513156-511900 [Xanthomonas translucens pv. translucens DSM 18974]
ATGAAAGGAAAGATAAGTAATGCATGCAAGCCAGACATCACTCCCATTCTTGTGGATGGCTTAGCATCGACAGCAACGCA
AGGTGCCGCAGATGACTCGGCTTCCAGGCTGCCACAGCAGGCGTTGCTTGATGGTCTGCAGGAAAGGCCGCAGGCCCTTA
AAAAATCCAATTCGGCCGATTGGTCTGCTCGCACTCTCCCGCAATGGGCGCCGGGTCCAGGGACATCATCAAAAGCCCTG
CTGATCCAATCGCCTCCTCACCCCACAAGTTCAGACGAGATGTTTGGACTGGGTGAGCTTCCAGCGCCCGGAAAAGCCCG
ATGGGAATATCTTACGAAAACCGAGAACTGGCATCCAGAGCGCCAGGAATTGCATAGCCGGCTATTGAGCCAAGCACGAA
CTGCATCCCTGCGCTTGGCCGAATCAATTGAGAGCGACGGCTACCCACCAACATTGTTCGCATTACGAGGCAATACTGCC
ACTGGTAAGACGCGTATAGCGACAAAGACGATTCCTGTGCTCGCAAATGCGCTCAAGAAGAGCAGTGGCGGCGGCTGCAT
TAATCCTGACATCTTTAAACGTTCACTAGCGGAATCGCAAGGAGAAGCAATGAAACTCAGTTCGGCGCAGGTACACGCCG
AATCATGCGTCCTCGCCGATCGGCTTGAAAACGAGCTTCGCTCGCAAAGGACCACAAGCGGTGCAATGGCCAGCATACTC
GTCGACAAACGACTGGCAAACACGCATGAGGTCGACAGCTACGTCAGTTTAGCCAAGGAGACAGGGCGCAAGGTCGAGTT
GTGCGATATCGATGCGCCTCTTGAGCGATCCCTTATGGGCGTACTTCAGAGAAGTCCGGGAGGTGATGATCCACGACCGC
CTTACGTGGCGGTTGCGAATGGATTTTCGACTGTCCGGAGCAACCGCTTAGATGTCATCGACAGGTTCCTGTCAAATCCA
ACCTTGGGAAGTTATCGCCTGTTCGGCACGAATGAAAAGGGTGAAAAAGTGATGGTTGCCAGCGTCGCCGATGGCGAACT
CAGCATTCACGACCCCCAGTTGTATGAGAGCATTACAGCTCCCGAGGACTTCAACTCGGGTGACAAAGGAGAACAGGTAA
TCGACACAGCGCTGATTGACCGTTTGAGCAACAGCATCGATGATCCAAAGCGTGCAACGGATGCACGTGCCGCCCTGGAG
AAATACAAGGGAATGACGTGGTCAAATGCTCTAGCGGCACACAGCTCATTGATCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT240642 WP_003863437.1 NZ_CP094841:c3968004-3967738 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT240642 NZ_LT604072:c511886-511590 [Xanthomonas translucens pv. translucens DSM 18974]
ATGACCCACTTAAAAGGCGCAGATGCACTTGCCCTGCATAAGAAACTCAAGGAGCGCAATGCCTCATTACGCAGTGCCGA
ACTTGATTCAGCAAAGGCGCTAGCCCATGAAAGCGGCAAAGAGCGCTTCAACCTCGAAAAATTGGAGAGCATTTGCGACA
CCACTCAAGCAGGGCGCATTACCGACCCGAACGATCGTCAGGCCATTTACGAACAAATGTATTATGTCGAGCATCCCAAA
GTCAGCACCTTGCAAGAATTCGCCCGCATTGTGGTGACGATTTCCTCATGGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BUV6

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References