240630

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2732261..2732622 Replicon chromosome
Accession NZ_CP094827
Organism Xanthomonas prunicola strain Arg-1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag MUG10_RS12105 Protein ID WP_010374872.1
Coordinates 2732488..2732622 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag MUG10_RS12100 Protein ID WP_010374875.1
Coordinates 2732261..2732413 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUG10_RS12070 (MUG10_12070) 2727350..2728033 - 684 WP_252161740.1 dTMP kinase -
MUG10_RS12075 (MUG10_12075) 2728480..2729022 - 543 WP_252161741.1 GTPase -
MUG10_RS12080 (MUG10_12080) 2729019..2729936 - 918 WP_252161742.1 hypothetical protein -
MUG10_RS12085 (MUG10_12085) 2730034..2730393 - 360 WP_252161743.1 roadblock/LC7 domain-containing protein -
MUG10_RS12090 (MUG10_12090) 2730457..2730909 - 453 WP_252161744.1 roadblock/LC7 domain-containing protein -
MUG10_RS12095 (MUG10_12095) 2731230..2732153 + 924 WP_252161745.1 arginase -
MUG10_RS12100 (MUG10_12100) 2732261..2732413 + 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
MUG10_RS12105 (MUG10_12105) 2732488..2732622 + 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
MUG10_RS12110 (MUG10_12110) 2732862..2733071 + 210 WP_017117799.1 CsbD family protein -
MUG10_RS12115 (MUG10_12115) 2733238..2734527 + 1290 WP_252161746.1 tryptophan--tRNA ligase -
MUG10_RS12120 (MUG10_12120) 2734598..2735603 + 1006 Protein_2361 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T240630 WP_010374872.1 NZ_CP094827:2732488-2732622 [Xanthomonas prunicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T240630 NZ_LT601384:c3327812-3327405 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT240630 WP_010374875.1 NZ_CP094827:2732261-2732413 [Xanthomonas prunicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT240630 NZ_LT601384:c3328059-3327793 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCAGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References