Detailed information of TA system TA240593

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tsbAT/-
• Location: 975158..975931
• Replicon: chromosome
• Accession: NZ_CP094814
• Organism: Staphylococcus agnetis strain IVB6175

Toxin (Protein)

• Gene name: tsbT
• Uniprot ID: -
• Locus tag: MUA52_RS04725
• Protein ID: WP_164671803.1
• Coordinates: 975776..975931 (+)
• Length: 52 a.a.

Antitoxin (Protein)

• Gene name: tsbA
• Uniprot ID: -
• Locus tag: MUA52_RS04720
• Protein ID: WP_105996312.1
• Coordinates: 975158..975757 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA52_RS04700 (MUA52_04695)	971462..972184	+	723	WP_262619230.1	amino acid ABC transporter ATP-binding protein	-
MUA52_RS04705 (MUA52_04700)	972356..973483	+	1128	WP_105996309.1	tRNA epoxyqueuosine(34) reductase QueG	-
MUA52_RS04710 (MUA52_04705)	973486..973956	+	471	WP_262619232.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
MUA52_RS04715 (MUA52_04710)	973971..975140	+	1170	WP_262619233.1	N-acetylglucosamine-6-phosphate deacetylase	-
MUA52_RS04720 (MUA52_04715)	975158..975757	+	600	WP_105996312.1	glucosamine-6-phosphate isomerase	Antitoxin
MUA52_RS04725 (MUA52_04720)	975776..975931	+	156	WP_164671803.1	SAS053 family protein	Toxin
MUA52_RS04730 (MUA52_04725)	976090..976491	+	402	WP_262619235.1	hypothetical protein	-
MUA52_RS04735 (MUA52_04730)	976648..978033	+	1386	WP_107391004.1	class II fumarate hydratase	-
MUA52_RS04740 (MUA52_04735)	978055..979581	+	1527	WP_105996314.1	exopolyphosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 52 a.a.
• Molecular weight: 6028.39 Da
• Isoelectric Point: 3.9242

>T240593 WP_164671803.1 NZ_CP094814:975776-975931 [Staphylococcus agnetis]
MSDEKHIEHENEMVDNFEDLVQLGKEMEQISETNDQDKVNQSHDPDIRSDQ

Nucleotide

• Length: 156 bp

>T240593 NZ_LT596221:c2617242-2617149 [Yersinia pseudotuberculosis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22431.40 Da
• Isoelectric Point: 5.6315

>AT240593 WP_105996312.1 NZ_CP094814:975158-975757 [Staphylococcus agnetis]
MAMNFKVFKDKDTVAVYAADIIRKQFNNNPTTIAGFHLSEEEAPVLDYLKRNVNDHAVDFSQIHILDYDKQASYFKALGV
PEKQIHEIPEEDEVEKFIEHKAKTKDNKGKLTLQVVSINNKGEFGVPVNNGLKPAREIFVVVTGSDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPDDVREYFTSLYA

Nucleotide

• Length: 600 bp

>AT240593 NZ_LT596221:2617148-2617242 [Yersinia pseudotuberculosis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA