Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 981272..982045 Replicon chromosome
Accession NZ_CP094809
Organism Staphylococcus agnetis strain IVB6197

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag MUA95_RS04745 Protein ID WP_164671803.1
Coordinates 981890..982045 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag MUA95_RS04740 Protein ID WP_262626753.1
Coordinates 981272..981871 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA95_RS04720 (MUA95_04710) 977576..978298 + 723 WP_262626749.1 amino acid ABC transporter ATP-binding protein -
MUA95_RS04725 (MUA95_04715) 978470..979597 + 1128 WP_262626750.1 tRNA epoxyqueuosine(34) reductase QueG -
MUA95_RS04730 (MUA95_04720) 979600..980070 + 471 WP_262626751.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
MUA95_RS04735 (MUA95_04725) 980085..981254 + 1170 WP_262626752.1 N-acetylglucosamine-6-phosphate deacetylase -
MUA95_RS04740 (MUA95_04730) 981272..981871 + 600 WP_262626753.1 glucosamine-6-phosphate isomerase Antitoxin
MUA95_RS04745 (MUA95_04735) 981890..982045 + 156 WP_164671803.1 SAS053 family protein Toxin
MUA95_RS04750 (MUA95_04740) 982204..982605 + 402 WP_262619235.1 hypothetical protein -
MUA95_RS04755 (MUA95_04745) 982762..984147 + 1386 WP_262626754.1 class II fumarate hydratase -
MUA95_RS04760 (MUA95_04750) 984169..985695 + 1527 WP_262626755.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 6028.39 Da        Isoelectric Point: 3.9242

>T240571 WP_164671803.1 NZ_CP094809:981890-982045 [Staphylococcus agnetis]
MSDEKHIEHENEMVDNFEDLVQLGKEMEQISETNDQDKVNQSHDPDIRSDQ

Download         Length: 156 bp

>T240571 NZ_LT594095:449464-449853 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22445.42 Da        Isoelectric Point: 5.6315

>AT240571 WP_262626753.1 NZ_CP094809:981272-981871 [Staphylococcus agnetis]
MAMNFKVFKDKDTVAVYAADIIRKQFNNNPTTIAGFHLSEEEAPVLDYLKRNVNDHAVDFSQIHILDYDKQASYFKALGI
PEKQIHEIPEEDEVEKFIEHKAKTKDNKGKLTLQVVSINNKGEFGVPVNNGLKPAREIFVVVTGSDKADVIKKLYEDNGN
TSFIPSSLKTHRMVNVILDEAAAQGLPDDVREYFTSLYA

Download         Length: 600 bp

>AT240571 NZ_LT594095:449200-449457 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References