Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 835944..836468 Replicon chromosome
Accession NZ_CP094741
Organism Staphylococcus chromogenes strain IVB6200

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag MUA19_RS03880 Protein ID WP_105987057.1
Coordinates 836115..836468 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MUA19_RS03875 Protein ID WP_105987058.1
Coordinates 835944..836114 (+) Length 57 a.a.

Genomic Context

MUA19_RS03850MUA19_RS03855MUA19_RS03860MUA19_RS03865MUA19_RS03870MUA19_RS03875MUA19_RS03880MUA19_RS03885MUA19_RS03890MUA19_RS03895MUA19_RS03900
Location: 831792..832265 (474 bp)
Type: Others
Protein ID: WP_262617282.1
Location: 832258..833736 (1479 bp)
Type: Others
Protein ID: WP_262617283.1
Location: 833733..834248 (516 bp)
Type: Others
Protein ID: WP_262617284.1
Location: 834245..834595 (351 bp)
Type: Others
Protein ID: WP_037577181.1
Location: 834711..835859 (1149 bp)
Type: Others
Protein ID: WP_105987059.1
Location: 835944..836114 (171 bp)
Type: Antitoxin
Protein ID: WP_105987058.1
Location: 836115..836468 (354 bp)
Type: Toxin
Protein ID: WP_105987057.1
Location: 836532..837536 (1005 bp)
Type: Others
Protein ID: WP_262617285.1
Location: 837617..837943 (327 bp)
Type: Others
Protein ID: WP_037577172.1
Location: 837946..838425 (480 bp)
Type: Others
Protein ID: WP_232195729.1
Location: 838400..839170 (771 bp)
Type: Others
Protein ID: WP_037577167.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MUA19_RS03850 (MUA19_03830)831792..832265+474WP_262617282.1PH domain-containing protein-
MUA19_RS03855 (MUA19_03835)832258..833736+1479WP_262617283.1PH domain-containing protein-
MUA19_RS03860 (MUA19_03840)833733..834248+516WP_262617284.1PH domain-containing protein-
MUA19_RS03865 (MUA19_03845)834245..834595+351WP_037577181.1holo-ACP synthase-
MUA19_RS03870 (MUA19_03850)834711..835859+1149WP_105987059.1alanine racemase-
MUA19_RS03875 (MUA19_03855)835944..836114+171WP_105987058.1type II toxin-antitoxin system antitoxin MazEAntitoxin
MUA19_RS03880 (MUA19_03860)836115..836468+354WP_105987057.1type II toxin-antitoxin system PemK/MazF family toxinToxin
MUA19_RS03885 (MUA19_03865)836532..837536+1005WP_262617285.1PP2C family protein-serine/threonine phosphatase-
MUA19_RS03890 (MUA19_03870)837617..837943+327WP_037577172.1anti-sigma factor antagonist-
MUA19_RS03895 (MUA19_03875)837946..838425+480WP_232195729.1anti-sigma B factor RsbW-
MUA19_RS03900 (MUA19_03880)838400..839170+771WP_037577167.1RNA polymerase sigma factor SigB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13106.38 Da        Isoelectric Point: 10.5461

>T240119 WP_105987057.1 NZ_CP094741:836115-836468 [Staphylococcus chromogenes]
MKRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRT
VDKKRLKEKLTFLSDKKMREVNAALGISLGLHMNQHK

Download         Length: 354 bp

>T240119 NZ_LS992166:c627463-626999 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6267.91 Da        Isoelectric Point: 4.2313

>AT240119 WP_105987058.1 NZ_CP094741:835944-836114 [Staphylococcus chromogenes]
MSAFNQTRVKSLEQSLKEGYVQMADLNLSLATEAYSVECEACDCNESHLLSNHKDD

Download         Length: 171 bp

>AT240119 NZ_LS992166:c627798-627463 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References