Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TsdAT/- |
| Location | 841648..842169 | Replicon | chromosome |
| Accession | NZ_CP094736 | ||
| Organism | Staphylococcus delphini strain IVB6222 | ||
Toxin (Protein)
| Gene name | TsdT | Uniprot ID | - |
| Locus tag | MUA33_RS03995 | Protein ID | WP_262611912.1 |
| Coordinates | 841948..842169 (+) | Length | 74 a.a. |
Antitoxin (Protein)
| Gene name | TsdA | Uniprot ID | A0A2A4GP16 |
| Locus tag | MUA33_RS03990 | Protein ID | WP_019165818.1 |
| Coordinates | 841648..841935 (+) | Length | 96 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA33_RS03965 (MUA33_03955) | 836913..837716 | + | 804 | WP_262611909.1 | hydroxyethylthiazole kinase | - |
| MUA33_RS03970 (MUA33_03960) | 837706..838344 | + | 639 | WP_096649784.1 | thiamine phosphate synthase | - |
| MUA33_RS03975 (MUA33_03965) | 838433..839299 | + | 867 | WP_096543018.1 | membrane protein insertase YidC | - |
| MUA33_RS03980 (MUA33_03970) | 839353..840009 | - | 657 | WP_262611910.1 | HD domain-containing protein | - |
| MUA33_RS03985 (MUA33_03975) | 840030..841520 | - | 1491 | WP_096597966.1 | cardiolipin synthase | - |
| MUA33_RS03990 (MUA33_03980) | 841648..841935 | + | 288 | WP_019165818.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
| MUA33_RS03995 (MUA33_03985) | 841948..842169 | + | 222 | WP_262611912.1 | heavy metal-associated domain-containing protein | Toxin |
| MUA33_RS04000 (MUA33_03990) | 842173..842379 | + | 207 | WP_262611913.1 | cation transporter | - |
| MUA33_RS04005 (MUA33_03995) | 842480..844660 | + | 2181 | WP_262611914.1 | heavy metal translocating P-type ATPase | - |
| MUA33_RS04010 (MUA33_04000) | 844746..844892 | + | 147 | WP_014613367.1 | Lmo0850 family protein | - |
| MUA33_RS04015 (MUA33_04005) | 845657..846418 | + | 762 | WP_262631156.1 | peptidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 74 a.a. Molecular weight: 8133.21 Da Isoelectric Point: 4.1528
>T240108 WP_262611912.1 NZ_CP094736:841948-842169 [Staphylococcus delphini]
MENGYVKVTQLTTEAQQQQLSDRLLRLIGVESVVIDLATQSLTLTYDTPANLNTIEKEIYDAGFPVIQSYKGV
MENGYVKVTQLTTEAQQQQLSDRLLRLIGVESVVIDLATQSLTLTYDTPANLNTIEKEIYDAGFPVIQSYKGV
Download Length: 222 bp
>T240108 NZ_LS483519:c1054403-1053669 [Mycoplasma mycoides subsp. capri]
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
Antitoxin
Download Length: 96 a.a. Molecular weight: 11000.61 Da Isoelectric Point: 6.7507
>AT240108 WP_019165818.1 NZ_CP094736:841648-841935 [Staphylococcus delphini]
MTEQAHHSEEIKRNLKSRLNRIEGQVKAINRMIDEDVYCDDVLTQIRATRSALNSVASRLLDHHMKGCIMHKIDAGHQDE
AMEELLVTFQKLMKD
MTEQAHHSEEIKRNLKSRLNRIEGQVKAINRMIDEDVYCDDVLTQIRATRSALNSVASRLLDHHMKGCIMHKIDAGHQDE
AMEELLVTFQKLMKD
Download Length: 288 bp
>AT240108 NZ_LS483519:c1055102-1054503 [Mycoplasma mycoides subsp. capri]
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|