Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TsdAT/- |
| Location | 880255..880776 | Replicon | chromosome |
| Accession | NZ_CP094734 | ||
| Organism | Staphylococcus delphini strain IVB6245 | ||
Toxin (Protein)
| Gene name | TsdT | Uniprot ID | - |
| Locus tag | MUA22_RS03945 | Protein ID | WP_096543014.1 |
| Coordinates | 880555..880776 (+) | Length | 74 a.a. |
Antitoxin (Protein)
| Gene name | TsdA | Uniprot ID | A0A2A4GP16 |
| Locus tag | MUA22_RS03940 | Protein ID | WP_019165818.1 |
| Coordinates | 880255..880542 (+) | Length | 96 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA22_RS03915 (MUA22_03915) | 875515..876318 | + | 804 | WP_262613371.1 | hydroxyethylthiazole kinase | - |
| MUA22_RS03920 (MUA22_03920) | 876308..876946 | + | 639 | WP_096556492.1 | thiamine phosphate synthase | - |
| MUA22_RS03925 (MUA22_03925) | 877035..877901 | + | 867 | WP_262613372.1 | membrane protein insertase YidC | - |
| MUA22_RS03930 (MUA22_03930) | 877956..878612 | - | 657 | WP_262613373.1 | HD domain-containing protein | - |
| MUA22_RS03935 (MUA22_03935) | 878633..880123 | - | 1491 | WP_262613374.1 | cardiolipin synthase | - |
| MUA22_RS03940 (MUA22_03940) | 880255..880542 | + | 288 | WP_019165818.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
| MUA22_RS03945 (MUA22_03945) | 880555..880776 | + | 222 | WP_096543014.1 | heavy metal-associated domain-containing protein | Toxin |
| MUA22_RS03950 (MUA22_03950) | 880780..880986 | + | 207 | WP_019165820.1 | cation transporter | - |
| MUA22_RS03955 (MUA22_03955) | 881087..883267 | + | 2181 | WP_262613375.1 | heavy metal translocating P-type ATPase | - |
| MUA22_RS03960 (MUA22_03960) | 883353..883499 | + | 147 | WP_014613367.1 | Lmo0850 family protein | - |
| MUA22_RS03965 (MUA22_03965) | 884468..885196 | + | 729 | WP_262613376.1 | peptidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 74 a.a. Molecular weight: 8107.18 Da Isoelectric Point: 4.3480
>T240105 WP_096543014.1 NZ_CP094734:880555-880776 [Staphylococcus delphini]
MENGYVKVTQLTTEAQQQQLSDRLLRLIGVESVVIDLATQSLTLTYDTPANLNTIEKEIYDAGFPVIQSHKGV
MENGYVKVTQLTTEAQQQQLSDRLLRLIGVESVVIDLATQSLTLTYDTPANLNTIEKEIYDAGFPVIQSHKGV
Download Length: 222 bp
>T240105 NZ_LS483516:c1047665-1046931 [Mycoplasma mycoides subsp. capri]
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
Antitoxin
Download Length: 96 a.a. Molecular weight: 11000.61 Da Isoelectric Point: 6.7507
>AT240105 WP_019165818.1 NZ_CP094734:880255-880542 [Staphylococcus delphini]
MTEQAHHSEEIKRNLKSRLNRIEGQVKAINRMIDEDVYCDDVLTQIRATRSALNSVASRLLDHHMKGCIMHKIDAGHQDE
AMEELLVTFQKLMKD
MTEQAHHSEEIKRNLKSRLNRIEGQVKAINRMIDEDVYCDDVLTQIRATRSALNSVASRLLDHHMKGCIMHKIDAGHQDE
AMEELLVTFQKLMKD
Download Length: 288 bp
>AT240105 NZ_LS483516:c1048364-1047765 [Mycoplasma mycoides subsp. capri]
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|