Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 913759..914283 Replicon chromosome
Accession NZ_CP094725
Organism Staphylococcus felis strain IVB6254

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag MUA17_RS04195 Protein ID WP_115940350.1
Coordinates 914059..914283 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag MUA17_RS04190 Protein ID WP_103207284.1
Coordinates 913759..914046 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA17_RS04165 (MUA17_04170) 908915..909715 + 801 WP_262633049.1 hydroxyethylthiazole kinase -
MUA17_RS04170 (MUA17_04175) 909718..910356 + 639 WP_262633050.1 thiamine phosphate synthase -
MUA17_RS04175 (MUA17_04180) 910444..911304 + 861 WP_103207289.1 membrane protein insertase YidC -
MUA17_RS04180 (MUA17_04185) 911472..912119 - 648 WP_262633051.1 HD domain-containing protein -
MUA17_RS04185 (MUA17_04190) 912135..913625 - 1491 WP_262633053.1 cardiolipin synthase -
MUA17_RS04190 (MUA17_04195) 913759..914046 + 288 WP_103207284.1 copper-sensing transcriptional repressor CsoR Antitoxin
MUA17_RS04195 (MUA17_04200) 914059..914283 + 225 WP_115940350.1 heavy-metal-associated domain-containing protein Toxin
MUA17_RS04200 (MUA17_04205) 914285..914491 + 207 WP_103207281.1 cation transporter -
MUA17_RS04205 (MUA17_04210) 914624..916807 + 2184 WP_262633054.1 heavy metal translocating P-type ATPase -
MUA17_RS04210 (MUA17_04215) 916896..917036 + 141 WP_167388982.1 Lmo0850 family protein -
MUA17_RS04215 (MUA17_04220) 917170..918366 - 1197 WP_262633055.1 FtsW/RodA/SpoVE family cell cycle protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(12-90)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8381.32 Da        Isoelectric Point: 3.9930

>T240081 WP_115940350.1 NZ_CP094725:914059-914283 [Staphylococcus felis]
MYQSYVQVSNIQTENDKEALENRLSSMIGVLDVQIDINQQCVNLEYETPANLNTLEKEIYDAGFPVINSFKGGH

Download         Length: 225 bp

>T240081 NZ_LS483496:689580-689984 [Haemophilus influenzae]
ATGATTTATATGTTAGACACCAATATCATTATTTATTTAATGAAAAATCGCCCCAAAATTGTTGCCGAACGAGTATCACA
ATTATTGCCTAATGATCGCTTAGTTATCAGCTTTATTACTTATGCTGAACTTATTAAAGGCGCCTTTAGTAGTCAAAATT
ATGAGCAATCAATACGAGCAATAGAATTACTTACTGAACGAGTAAATGTACTATATCCCAATGAACAAATCTGTTTACAT
TATGGCAAATGGGCAAATACACTCAAAAAACAAGGGAGACCTATCGGAAATAATGATCTATGGATTGCTTGTCACGCATT
GAGTTTAAATGCTGTTCTTATTACACATAATGTAAAAGAATTTCAGCGTATTACAGATCTTCAGTGGCAAGATTGGACAA
AATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11005.63 Da        Isoelectric Point: 6.8618

>AT240081 WP_103207284.1 NZ_CP094725:913759-914046 [Staphylococcus felis]
MTEQAHHSDSIKRNLKSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATKLLDYHMKGCIMHKIENGSEQE
AMEELLVTFQKLMKD

Download         Length: 288 bp

>AT240081 NZ_LS483496:689347-689583 [Haemophilus influenzae]
ATGCTTGCTAAAGTGTTTCAAAGTGGTAACAGCCAAGCTGTTCGGATCCCGATGGACTTTCGTTTTGATGTCGATACCGT
AGAAATTTTCCGAAAGGAAAATGGGGATGTGGTATTACGCCCAGTTTCTAAAAAAACAGATGATTTTCTTGCGTTATTTG
AAGGATTTGATGAGACCTTTATTCAAGCACTTGAAGCGCGTGATGATTTACCGCCTCAGGAGCGAGAAAATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References