Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 1779107..1779629 | Replicon | chromosome |
Accession | NZ_CP094720 | ||
Organism | Staphylococcus sp. IVB6233 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | - |
Locus tag | MUA74_RS08890 | Protein ID | WP_262609113.1 |
Coordinates | 1779107..1779328 (-) | Length | 74 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | - |
Locus tag | MUA74_RS08895 | Protein ID | WP_262603714.1 |
Coordinates | 1779342..1779629 (-) | Length | 96 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MUA74_RS08870 (MUA74_08850) | 1775108..1776313 | + | 1206 | WP_262603710.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
MUA74_RS08875 | 1776394..1776534 | - | 141 | WP_262605150.1 | Lmo0850 family protein | - |
MUA74_RS08880 (MUA74_08855) | 1776620..1778800 | - | 2181 | WP_262603711.1 | heavy metal translocating P-type ATPase | - |
MUA74_RS08885 (MUA74_08860) | 1778901..1779104 | - | 204 | WP_262603712.1 | cation transporter | - |
MUA74_RS08890 (MUA74_08865) | 1779107..1779328 | - | 222 | WP_262609113.1 | heavy metal-associated domain-containing protein | Toxin |
MUA74_RS08895 (MUA74_08870) | 1779342..1779629 | - | 288 | WP_262603714.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
MUA74_RS08900 (MUA74_08875) | 1779773..1781263 | + | 1491 | WP_262609114.1 | cardiolipin synthase | - |
MUA74_RS08905 (MUA74_08880) | 1781284..1781934 | + | 651 | WP_262609115.1 | HD domain-containing protein | - |
MUA74_RS08910 (MUA74_08885) | 1781997..1782866 | - | 870 | WP_262603717.1 | membrane protein insertase YidC | - |
MUA74_RS08915 (MUA74_08890) | 1782955..1783593 | - | 639 | WP_262605151.1 | thiamine phosphate synthase | - |
MUA74_RS08920 (MUA74_08895) | 1783583..1784389 | - | 807 | WP_262603718.1 | hydroxyethylthiazole kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 74 a.a. Molecular weight: 8299.26 Da Isoelectric Point: 4.1813
>T240066 WP_262609113.1 NZ_CP094720:c1779328-1779107 [Staphylococcus sp. IVB6233]
VHSKVWLSGLSSEEQKQQLESRLRDMIGVETAEVDIDKQIVILTYETPANLNTLEKEIYDAGYPVINSYKGED
VHSKVWLSGLSSEEQKQQLESRLRDMIGVETAEVDIDKQIVILTYETPANLNTLEKEIYDAGYPVINSYKGED
Download Length: 222 bp
>T240066 NZ_LS483486:384848-385030 [Haemophilus influenzae]
ATGTACGAGATTCTCTTTTACAGAGACCAAAATGACATTGAGCCAGTGAAAGAGTATCTGCTATCTCTGGCTCAAAATGA
AAGCAAAGATAGTCGAATTAAACTGAATAAAATTCGAGATTATGTAATCCAAACTGCCCAACAACGCTTAAGTGAATTAA
AAGAGAGATTGAAAAATGAATAA
ATGTACGAGATTCTCTTTTACAGAGACCAAAATGACATTGAGCCAGTGAAAGAGTATCTGCTATCTCTGGCTCAAAATGA
AAGCAAAGATAGTCGAATTAAACTGAATAAAATTCGAGATTATGTAATCCAAACTGCCCAACAACGCTTAAGTGAATTAA
AAGAGAGATTGAAAAATGAATAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10929.52 Da Isoelectric Point: 6.6368
>AT240066 WP_262603714.1 NZ_CP094720:c1779629-1779342 [Staphylococcus sp. IVB6233]
MIEHANHSEVTKRNLQSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVASKLLEHHMKGCILHKVEGGNEQE
AMDELLVTFQKLMKD
MIEHANHSEVTKRNLQSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVASKLLEHHMKGCILHKVEGGNEQE
AMDELLVTFQKLMKD
Download Length: 288 bp
>AT240066 NZ_LS483486:385023-385319 [Haemophilus influenzae]
ATGAATAAAATTAGCCCATTAGGTTCAAATTGGAATGAGTTTGAACAGCAAATTTTCAATGAAGAAGAAATCCGAGAAAG
TAATTTACGTGTAGCCTTAATTAAAGAATTGATTACTTCTCGCCAGCAACTTGGGATTTCCCAAAAACAACTTGAAACCT
TAAGCGGTGTGAAGCAACCTATGATTGCACGCATTGAAAAAGGACAAACGAATCCTCAGCTTGAAACGTTGTTAAAATTG
CTCGCTCCTTTAGGGAAAACCCTGTCGATTGTGCCTCTAAGGGTAAAAAATGCCTAA
ATGAATAAAATTAGCCCATTAGGTTCAAATTGGAATGAGTTTGAACAGCAAATTTTCAATGAAGAAGAAATCCGAGAAAG
TAATTTACGTGTAGCCTTAATTAAAGAATTGATTACTTCTCGCCAGCAACTTGGGATTTCCCAAAAACAACTTGAAACCT
TAAGCGGTGTGAAGCAACCTATGATTGCACGCATTGAAAAAGGACAAACGAATCCTCAGCTTGAAACGTTGTTAAAATTG
CTCGCTCCTTTAGGGAAAACCCTGTCGATTGTGCCTCTAAGGGTAAAAAATGCCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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