Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 1676093..1676615 | Replicon | chromosome |
Accession | NZ_CP094718 | ||
Organism | Staphylococcus sp. IVB6240 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | - |
Locus tag | MUA88_RS08320 | Protein ID | WP_262605385.1 |
Coordinates | 1676093..1676314 (-) | Length | 74 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | - |
Locus tag | MUA88_RS08325 | Protein ID | WP_262603714.1 |
Coordinates | 1676328..1676615 (-) | Length | 96 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MUA88_RS08300 (MUA88_08285) | 1672094..1673299 | + | 1206 | WP_262603710.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
MUA88_RS08305 | 1673380..1673520 | - | 141 | WP_262605150.1 | Lmo0850 family protein | - |
MUA88_RS08310 (MUA88_08290) | 1673606..1675786 | - | 2181 | WP_262605384.1 | heavy metal translocating P-type ATPase | - |
MUA88_RS08315 (MUA88_08295) | 1675887..1676090 | - | 204 | WP_262603712.1 | cation transporter | - |
MUA88_RS08320 (MUA88_08300) | 1676093..1676314 | - | 222 | WP_262605385.1 | heavy metal-associated domain-containing protein | Toxin |
MUA88_RS08325 (MUA88_08305) | 1676328..1676615 | - | 288 | WP_262603714.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
MUA88_RS08330 (MUA88_08310) | 1676759..1678249 | + | 1491 | WP_262605386.1 | cardiolipin synthase | - |
MUA88_RS08335 (MUA88_08315) | 1678270..1678920 | + | 651 | WP_262605387.1 | HD domain-containing protein | - |
MUA88_RS08340 (MUA88_08320) | 1678983..1679852 | - | 870 | WP_262603717.1 | membrane protein insertase YidC | - |
MUA88_RS08345 (MUA88_08325) | 1679941..1680579 | - | 639 | WP_262605151.1 | thiamine phosphate synthase | - |
MUA88_RS08350 (MUA88_08330) | 1680569..1681375 | - | 807 | WP_262605388.1 | hydroxyethylthiazole kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 74 a.a. Molecular weight: 8303.25 Da Isoelectric Point: 4.1813
>T240059 WP_262605385.1 NZ_CP094718:c1676314-1676093 [Staphylococcus sp. IVB6240]
VHSKVWLSGLSSEEQKQQLESRLRDMIGVETAEVDIDKQIVILTYETPANLNTLEKEIYDAGYTVINSYKGED
VHSKVWLSGLSSEEQKQQLESRLRDMIGVETAEVDIDKQIVILTYETPANLNTLEKEIYDAGYTVINSYKGED
Download Length: 222 bp
>T240059 NZ_LS483484:c2305686-2305582 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10929.52 Da Isoelectric Point: 6.6368
>AT240059 WP_262603714.1 NZ_CP094718:c1676615-1676328 [Staphylococcus sp. IVB6240]
MIEHANHSEVTKRNLQSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVASKLLEHHMKGCILHKVEGGNEQE
AMDELLVTFQKLMKD
MIEHANHSEVTKRNLQSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVASKLLEHHMKGCILHKVEGGNEQE
AMDELLVTFQKLMKD
Download Length: 288 bp
>AT240059 NZ_LS483484:2305489-2305527 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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