Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 966090..966893 Replicon chromosome
Accession NZ_CP094715
Organism Staphylococcus pasteuri strain IVB6198

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag MUA61_RS04800 Protein ID WP_017638030.1
Coordinates 966717..966893 (+) Length 59 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag MUA61_RS04795 Protein ID WP_070454063.1
Coordinates 966090..966689 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA61_RS04775 (MUA61_04775) 961989..963449 + 1461 WP_070454069.1 ABC transporter substrate-binding protein/permease -
MUA61_RS04780 (MUA61_04780) 963442..964164 + 723 WP_029056292.1 amino acid ABC transporter ATP-binding protein -
MUA61_RS04785 (MUA61_04785) 964307..965437 + 1131 WP_046466852.1 tRNA epoxyqueuosine(34) reductase QueG -
MUA61_RS04790 (MUA61_04790) 965438..965908 + 471 WP_017638028.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
MUA61_RS04795 (MUA61_04795) 966090..966689 + 600 WP_070454063.1 glucosamine-6-phosphate isomerase Antitoxin
MUA61_RS04800 (MUA61_04800) 966717..966893 + 177 WP_017638030.1 SAS053 family protein Toxin
MUA61_RS04805 (MUA61_04805) 967045..967437 + 393 WP_017638031.1 hypothetical protein -
MUA61_RS04810 (MUA61_04810) 967593..968978 + 1386 WP_070454060.1 class II fumarate hydratase -
MUA61_RS04815 (MUA61_04815) 969038..969868 - 831 WP_262552920.1 RluA family pseudouridine synthase -
MUA61_RS04820 (MUA61_04820) 970048..971160 + 1113 WP_029056288.1 GAF domain-containing sensor histidine kinase -
MUA61_RS04825 (MUA61_04825) 971181..971804 + 624 WP_262552923.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(125-195)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6787.12 Da        Isoelectric Point: 3.8537

>T240047 WP_017638030.1 NZ_CP094715:966717-966893 [Staphylococcus pasteuri]
MTQNKDSKTNYHEEENAMVTDLDDLKDLGKEMEQISEENDEDKLNQSHDSDVRSDLEE

Download         Length: 177 bp

>T240047 NZ_LS483482:971402-971614 [Staphylococcus lugdunensis]
GTGGAAAAGCGATTAATTTATATTACAAATGTGACTAGTGAAGACGACTTGGAAAACTTACGAACAAGGTTATTAGAGAT
GATTGGTGTTAATGAAGTAGTGATCAATTTTGATGAACGTGCAGTTAATGTTACTTTTGAAACACCAACTAATTTAAATG
CACTTGAAAAAGAAATATATGATGCTGGCTATCATGCTATAGATGATTTATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22632.51 Da        Isoelectric Point: 4.8610

>AT240047 WP_070454063.1 NZ_CP094715:966090-966689 [Staphylococcus pasteuri]
MAMNFKVFEDKQRVAEYTADILRKQFNNNPMTIAGVHLTKDHAPVLDELKKNVELHAVDFSQINILDYDENNSYYEALGV
PQSQIYSLSYNQDANEFISDKIKTKENKGKLVLQVVSIDENGNLDVSVRQGLLEAREIFLVVTGSNKREVVEKLYNENGK
SNYEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA

Download         Length: 600 bp

>AT240047 NZ_LS483482:971096-971389 [Staphylococcus lugdunensis]
TTGAACGAACAAGATCATGCACATCATTCTAAAATTGTAAAAGCAAATTTAAAATCTAGATTAAATCGTATAGAAGGACA
AGTGCGGGCAATTAATCGCATGGTTGAAGATGATGTTTATTGTGATGATGTGTTAACACAAATAAGAGCAACACGCTCAG
CATTAACGAGTGTAGCAACAAAACTATTAGAGCATCATATGAAAAGTTGTATCATGGATAAAATAAACGATGGGCAGGAA
GTTGAAGCGATGGAGGAATTGCTAGTTACATTTCAAAAAATGCTAAAAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References